Nutrition and Neuropsychiatric Symptom Dimensions (NutriPsy)

The NutriPsy team aims to advance the understanding of the relationship between nutrition and mental health, focusing on how nutritional imbalances contribute to neuropsychiatric symptoms through their impact on inflammatory processes. To this end, we have designed a translational and integrative research program with three core objectives:


  1. Mechanistic Insights: Investigate how inflammation, influenced by dietary habits, triggers neuropsychiatric symptoms—particularly depression—and contributes to resistance to antidepressants. This includes linking inflammation to specific clinical dimensions.

  2. Environmental and Genetic Influences: Examine the role of environmental factors and genetic variants associated with inflammation in the onset of depressive symptoms and their response to antidepressants, in both clinical and preclinical models of nutritional imbalance.

  3. Targeted Treatment Strategies: propose innovative and targeted treatment strategies, based on personalized nutritional interventions, guided by the environmental, clinical (symptomatic dimensions), biological/inflammatory and nutritional profiles of patients, previously identified. This research is a pivotal step towards advancing precision medicine in mental health, addressing the critical need for effective treatments, as standard therapies currently fail in approximately one-third of cases.