Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption, via hippocampal thyroid hormone signaling
Jean-Christophe Helbling, Rachel Ginieis, Pierre Mortessagne, Mariano Ruiz-Gayo, Ioannis Bakoyiannis, Eva-Gunnel Ducourneau, Dominique Ciocca, Illona-Marie Bouleté, Alexandre Favereaux, Aurélia Ces, Enrica Montalban, Lucile Capuron, Freddy Jeanneteau, Guillaume Ferreira, Etienne Challet, Marie-Pierre Moisan
Molecular Metabolism. 2024-12-01
10.1016/j.molmet.2024.102061

Impact of dietary vitamin A on striatal function in adult rats.
Anaïs Marie, Rémi Kinet, Jean‐Christophe Helbling, Morgane Darricau, Serge Alfos, Mathieu Di Miceli, Maria‐Florencia Angelo, Aline Foury, Emmanuel Richard, Pierre Trifilieff, Nicolas P. Mallet, Clementine Bosch‐Bouju
The FASEB Journal. 2023-07-01
10.1096/fj.202300133r

Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency
Julie Brossaud, Clémentine Bosch-Bouju, Nathalie Marissal-Arvy, Marie-Neige Campas-Lebecque, Jean-Christophe Helbling, Scott P. Webster, Brian R. Walker, Xavier Fioramonti, Guillaume Ferreira, Pascal Barat, Jean-Benoît Corcuff, Marie-Pierre Moisan
Diabetologia. 2023-06-10
10.1007/s00125-023-05942-3

Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies
Essi F. Biyong, Cyntia Tremblay, Manon Leclerc, Vicky Caron, Serge Alfos, Jean-Christophe Helbling, Léa Rodriguez, Vincent Pernet, David A. Bennett, Véronique Pallet, Frédéric Calon
Neurobiology of Disease. 2021-12-01
10.1016/j.nbd.2021.105542

Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus.
Jean-Christophe Helbling, Kenichiro Kinouchi, Pierre Trifilieff, Paolo Sassone-Corsi, Marie-Pierre Moisan
Curr Protoc. 2021-02
10.1002/cpz1.33

Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens.
Aline Foury, Anne Collin, Jean-Christophe Helbling, Christine Leterrier, Marie-Pierre Moisan, Laurence A. Guilloteau
Sci Rep. 2020-11-26
10.1038/s41598-020-77732-5

Dietary vitamin A supplementation prevents early obesogenic diet-induced microbiota, neuronal and cognitive alterations
Essi F. Biyong, Serge Alfos, Fabien Dumetz, Jean-Christophe Helbling, Agnès Aubert, Julie Brossaud, Aline Foury, Marie-Pierre Moisan, Sophie Layé, Emmanuel Richard, Elaine Patterson, Kiera Murphy, Kieran Rea, Catherine Stanton, Harriët Schellekens, John F. Cryan, Lucile Capuron, Véronique Pallet, Guillaume Ferreira
Int J Obes. 2020-11-22
10.1038/s41366-020-00723-z

Reshaping circadian metabolism in the suprachiasmatic nucleus and prefrontal cortex by nutritional challenge
Paola Tognini, Muntaha Samad, Kenichiro Kinouchi, Yu Liu,Jean-Christophe Helbling, Marie-Pierre Moisan, Kristin L. Eckel-Mahan, Pierre Baldi, Paolo Sassone-Corsi
Proc Natl Acad Sci USA. 2020-11-10
10.1073/pnas.2016589117

Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits.
Fabien Ducrocq, Roman Walle, Andrea Contini, Asma Oummadi, Baptiste Caraballo, Suzanne van der Veldt, Marie-Lou Boyer, Frank Aby, Tarson Tolentino-Cortez, Jean-Christophe Helbling, Lucy Martine, Stéphane Grégoire, Stéphanie Cabaret, Sylvie Vancassel, Sophie Layé, Jing Xuan Kang, Xavier Fioramonti, Olivier Berdeaux, Gabriel Barreda-Gómez, Elodie Masson, Guillaume Ferreira, David W.L. Ma, Clementine Bosch-Bouju, Véronique De Smedt-Peyrusse, Pierre Trifilieff
Cell Metabolism. 2020-04-01
10.1016/j.cmet.2020.02.012

Unraveling the effects of the gut microbiota composition and function on horse endurance physiology.
Sandra Plancade, Allison Clark, Catherine Philippe, Jean-Christophe Helbling, Marie-Pierre Moisan, Diane Esquerré, Laurence Le Moyec, Céline Robert, Eric Barrey, Núria Mach
Sci Rep. 2019-07-03
10.1038/s41598-019-46118-7

Pharmacological restoration of gut barrier function in stressed neonates partially reverses long-term alterations associated with maternal separation
Marion Rincel, Maïwenn Olier, Amandine Minni, Camille Monchaux de Oliveira, Yann Matime, Eric Gaultier, Isabelle Grit, Jean-Christophe Helbling, Anna Maria Costa, Amandine Lépinay, Marie-Pierre Moisan, Sophie Layé, Laurent Ferrier, Patricia Parnet, Vassilia Theodorou, Muriel Darnaudéry
Psychopharmacology. 2019-05-01
10.1007/s00213-019-05252-w

Corticosteroid-Binding Globulin deficiency specifically impairs contextual and recognition memory consolidation in male mice
Gabriela de Medeiros, Pauline Lafenêtre, Yoottana Janthakhin, Juan-Carlos Cerpa, Chun-Lei Zhang, Marishka Mehta, Pierre Mortessagne, Jean-Christophe Helbling, Guillaume Ferreira, Marie-Pierre Moisan
Neuroendocrinology. 2019-03-25
10.1159/000499827

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner
Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira C, Helbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M.
Brain Behav Immun.. 2019-03-11
10.1016/j.bbi.2019.03.006

Insulin treatment partially prevents cognitive and hippocampal alterations as well as glucocorticoid dysregulation in early-onset insulin-deficient diabetic rats.
Nathalie Marissal-Arvy, Marie-Neige Campas, Audrey Semont, Céline Ducroix-Crepy, Marie-Christine Beauvieux, Julie Brossaud, Jean-Benoit Corcuff, Jean-Christophe Helbling, Sylvie Vancassel, Anne-Karine Bouzier-Sore, Katia Touyarot, Guillaume Ferreira, Pascal Barat, Marie-Pierre Moisan
Psychoneuroendocrinology. 2018-07-01
10.1016/j.psyneuen.2018.04.016

Retinoic acid increases glucocorticoid receptor phosphorylation via cyclin-dependent kinase
Julie Brossaud ; Hélène Roumes ; Jean-Christophe Helbling ; Marie-Pierre Moisan ; Véronique Pallet ; Guillaume Ferreira ; Essi-Fanny Biyong ; Anabelle Redonnet; Jean-Benoît Corcuff
Molecular and Cellular Neuroscience.
https://doi.org/10.1016/j.mcn.2017.05.001

Retinoic acid increases glucocorticoid receptor phosphorylation via cyclin-dependent kinase 5.
Julie Brossaud, Hélène Roumes, Jean-Christophe Helbling, Marie-Pierre Moisan, Véronique Pallet, Guillaume Ferreira, Essi-Fanny Biyong, Anabelle Redonnet, Jean-Benoît Corcuff
Molecular and Cellular Neuroscience. 2017-07-01
10.1016/j.mcn.2017.05.001

Nasal airway epithelial cell IL-6 and FKBP51 gene expression and steroid sensitivity in asthmatic children.
Michael Fayon, Aurelie Lacoste-Rodrigues, Pascal Barat, Jean-Christophe Helbling, Fabienne Nacka, Patrick Berger, Marie-Pierre Moisan, Jean-Benoit Corcuff
PLoS ONE. 2017-05-11
10.1371/journal.pone.0177051

Diabetes and Insulin Injection Modalities: Effects on Hepatic and Hippocampal Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Juvenile Diabetic Male Rats.
Véronica Rougeon, Marie-Pierre Moisan, Nicole Barthe, Marie-Christine Beauvieux, Jean-Christophe Helbling, Véronique Pallet, Nathalie Marissal-Arvy, Pascal Barat
Front. Endocrinol.. 2017-04-18
10.3389/fendo.2017.00081

Chronic stress does not further exacerbate the abnormal psychoneuroendocrine phenotype of Cbg-deficient male mice.
Gabriela F. de Medeiros, Amandine M. Minni, Jean-Christophe Helbling, Marie-Pierre Moisan
Psychoneuroendocrinology. 2016-08-01
10.1016/j.psyneuen.2016.04.014

Role of corticosteroid binding globulin in emotional reactivity sex differences in mice.
A.M. Minni, G.F. de Medeiros, J.C. Helbling, A. Duittoz, N. Marissal-Arvy, A. Foury, V. De Smedt-Peyrusse, V. Pallet, M.P. Moisan
Psychoneuroendocrinology. 2014-12-01
10.1016/j.psyneuen.2014.07.029

Role of corticosteroid binding globulin in the fast actions of glucocorticoids on the brain.
M.P. Moisan, A.M. Minni, G. Dominguez, J.C. Helbling, A. Foury, N. Henkous, R. Dorey, D. Béracochéa
Steroids. 2014-03-01
10.1016/j.steroids.2013.10.013

Stress and glucocorticoid regulation of NR4A genes in mice.
Jean-Christophe Helbling, Amandine M. Minni, Véronique Pallet, Marie-Pierre Moisan
Journal of Neuroscience Research. 2014-02-19
10.1002/jnr.23366

Corticosteroid-binding globulin contributes to the neuroendocrine phenotype of mice selected for extremes in stress reactivity.
Gabriele E Mattos, Jan-Michael Heinzmann, Stefanie Norkowski, Jean-Christophe Helbling, Amandine M Minni, Marie-Pierre Moisan, Chadi Touma
Journal of Endocrinology. 2013-09-17
10.1530/JOE-13-0255

Critical role of plasma corticosteroid-binding-globulin during stress to promote glucocorticoid delivery to the brain: impact on memory retrieval.
Amandine M. Minni, Rodolphe Dorey, Christophe Piérard, Gaëlle Dominguez, Jean-Christophe Helbling, Aline Foury, Daniel Béracochéa, Marie-Pierre Moisan
Endocrinology. 2012-10-01
10.1210/en.2012-1485

Intrinsic expression of transcortin in neural cells of the mouse brain: a histochemical and molecular study.
Elena Sivukhina, Jean-Christophe Helbling, Amandine M. Minni, H. Hendrik Schäfer, Véronique Pallet, Gustav F. Jirikowski, Marie-Pierre Moisan
J Exp Biol. 2012-09-20
10.1242/jeb.076893

Maintaining RNA integrity in a homogeneous population of mammary epithelial cells isolated by Laser Capture Microdissection.
Claudia Bevilacqua, Samira Makhzami, Jean-Christophe Helbling, Pierre Defrenaix, Patrice Martin
BMC Cell Biol. 2010-12-01
10.1186/1471-2121-11-95

Terminal differentiation of goat mammary tissue during pregnancy requires the expression of genes involved in immune functions.
F. Faucon, E. Rebours, C. Bevilacqua, J.-C. Helbling, J. Aubert, S. Makhzami, S. Dhorne-Pollet, S. Robin, P. Martin
Physiological Genomics. 2009-12-01
10.1152/physiolgenomics.00032.2009

Persistence of plant DNA sequences in the blood of dairy cows fed with genetically modified (Bt176) and conventional corn silage.
Y. Bertheau, J. C. Helbling, M. N. Fortabat, S. Makhzami, I. Sotinel, C. Audéon, A. C. Nignol, A. Kobilinsky, L. Petit, P. Fach, P. Brunschwig, K. Duhem, P. Martin
J. Agric. Food Chem.. 2009-01-05
10.1021/jf802262c

The olig family: phylogenetic analysis and early gene expression in Xenopus tropicalis.
O. J. Bronchain, N. Pollet, Q. Ymlahi-Ouazzani, S. Dhorne-Pollet, J. C. Helbling, J. E. Lecarpentier, K. Percheron, M. Wegnez
Dev Genes Evol. 2007-06-07
10.1007/s00427-007-0158-z

Translational efficiency of casein transcripts in the mammary tissue of lactating ruminants.
Claudia Bevilacqua, Jean Christophe Helbling, Guy Miranda, Patrice Martin
Reprod. Nutr. Dev.. 2006-09-01
10.1051/rnd:2006028