Distinct Chrna5 mutations link excessive alcohol use to types I/II vulnerability profiles and IPN GABAergic neurons.
Léa Tochon, Nadia Henkous, Morgane Besson, Uwe Maskos, Vincent David
Transl Psychiatry. 2024-11-06
10.1038/s41398-024-03164-8

Chronic alcohol consumption shifts learning strategies and synaptic plasticity from hippocampus to striatum-dependent pathways
Léa Tochon, Rose-Marie Vouimba, Marc Corio, Nadia Henkous, Daniel Béracochéa, Jean-Louis Guillou, Vincent David
Front. Psychiatry. 2023-05-26
10.3389/fpsyt.2023.1129030

Impact of the gut microbiome on nicotine’s motivational effects and glial cells in the ventral tegmental area in male mice
Alina Lakosa, Anaïs Rahimian, Flavio Tomasi, Fabio Marti, Lauren M. Reynolds, Léa Tochon, Vincent David, Anne Danckaert, Candice Canonne, Sylvana Tahraoui, Fabrice de Chaumont, Benoît Forget, Uwe Maskos, Morgane Besson
Neuropsychopharmacol.. 2023-03-17
10.1038/s41386-023-01563-x

β4-Nicotinic Receptors Are Critically Involved in Reward-Related Behaviors and Self-Regulation of Nicotine Reinforcement
Marianne Husson, Lauriane Harrington, Léa Tochon, Yoon Cho, Inés Ibañez-Tallon, Uwe Maskos, Vincent David
J. Neurosci.. 2020-03-17
10.1523/JNEUROSCI.0356-19.2020

Targeting the Glucocorticoid Receptors During Alcohol Withdrawal to Reduce Protracted Neurocognitive Disorders.
Daniel Béracochéa, Nicole Mons and Vincent David
Front Psychiatry. 2019-09-18
10.3389/fpsyt.2019.00580

Morphine Reward Promotes Cue-Sensitive Learning: Implication of Dorsal Striatal CREB Activity.
Mathieu Baudonnat, Jean-Louis Guillou, Marianne Husson, Veronique D. Bohbot, Lars Schwabe, Vincent David
Front. Psychiatry. 2017-05-30
10.3389/fpsyt.2017.00087

Alcohol withdrawal induces long-lasting spatial working memory impairments: relationship with changes in corticosterone response in the prefrontal cortex.
Gaelle Dominguez, Catherine Belzung, Christophe Pierard, Vincent David, Nadia Henkous, Laurence Decorte, Nicole Mons, Daniel Beracochea
Addiction Biology. 2016-02-10
10.1111/adb.12371

Heads for learning, tails for memory: reward, reinforcement and a role of dopamine in determining behavioral relevance across multiple timescales.
Mathieu Baudonnat, Anna Huber, Vincent David, Mark E. Walton
Front. Neurosci.. 2013-01-01
10.3389/fnins.2013.00175

Involvement of protein degradation by the ubiquitin proteasome system in opiate addictive behaviors.
Nicolas Massaly, Lionel Dahan, Mathieu Baudonnat, Caroline Hovnanian, Khaoula Rekik, Marcello Solinas, Vincent David, Stéphane Pech, Jean-Marie Zajac, Pascal Roullet, Lionel Mouledous, Bernard Frances
Neuropsychopharmacol. 2012-11-21
10.1038/npp.2012.217

Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement
S Tolu, R Eddine, F Marti, V David, M Graupner, S Pons, M Baudonnat, M Husson, M Besson, C Reperant, J Zemdegs, C Pagès, Y A H Hay, B Lambolez, J Caboche, B Gutkin, A M Gardier, J-P Changeux, P Faure, U Maskos
Mol Psychiatry. 2012-07-03
10.1038/mp.2012.83

Disrupting effect of drug-induced reward on spatial but not cue-guided learning: implication of the striatal protein kinase A/cAMP response element-binding protein pathway.
M. Baudonnat, J.-L. Guillou, M. Husson, M. Vandesquille, M. Corio, L. Decorte, A. Faugere, Y. Porte, N. Mons, V. David
Journal of Neuroscience. 2011-11-16
10.1523/jneurosci.1787-11.2011

Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.
R. Exley, N. Maubourguet, V. David, R. Eddine, A. Evrard, S. Pons, F. Marti, S. Threlfell, P. Cazala, J. M. McIntosh, J.-P. Changeux, U. Maskos, S. J. Cragg, P. Faure
Proceedings of the National Academy of Sciences. 2011-04-18
10.1073/pnas.1103000108

Brain regional Fos expression elicited by the activation of mu- but not delta-opioid receptors of the ventral tegmental area: evidence for an implication of the ventral thalamus in opiate reward.
Vincent David, Audrey Matifas, Stéphanie Gavello-Baudy, Laurence Decorte, Brigitte L Kieffer, Pierre Cazala
Neuropsychopharmacol. 2007-09-26
10.1038/sj.npp.1301529

Long-term effects of chronic nicotine exposure on brain nicotinic receptors.
M. Besson, S. Granon, M. Mameli-Engvall, I. Cloez-Tayarani, N. Maubourguet, A. Cormier, P. Cazala, V. David, J.-P. Changeux, P. Faure
Proceedings of the National Academy of Sciences. 2007-04-30
10.1073/pnas.0702698104

Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: Dependence on cholinergic nicotinic and dopaminergic D1 receptors
Vincent David, Morgane Besson, Jean-Pierre Changeux, Sylvie Granon, Pierre Cazala
Neuropharmacology. 2006-06-01
10.1016/j.neuropharm.2006.02.003

Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors.
B. E. Molles, U. Maskos, S. Pons, M. Besson, P. Guiard, J.-P. Guilloux, A. Evrard, A. Cormier, M. Mameli-Engvall, I. Cloëz-Tayarani, H. Nakatani, N. Dufour, A.-P. Bemelmans, J. Mallet, P. Cazala, A. M. Gardier, V. David, P. Faure, S. Granon, J.-P. Changeux
JMN. 2006-01-01
10.1385/jmn:30:1:105

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J.-P. Guilloux, A. Evrard, P. Cazala, A. Cormier, M. Mameli-Engvall, N. Dufour, I. Cloëz-Tayarani, A.-P. Bemelmans, J. Mallet, A. M. Gardier, V. David, P. Faure, S. Granon, J.-P. Changeux
Nature. 2005-07-01
10.1038/nature03694

Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice.
V David
Neuropsychopharmacology. 2001-03-01
10.1016/s0893-133x(00)00205-0