The role of gene-environment interactions in social dysfunction: focus on preclinical evidence from mouse studies
Giulia Castellano, Johana Bonnet Da Silva, Susanna Pietropaolo
Neuropharmacology. 2024-10-01
10.1016/j.neuropharm.2024.110179

Autistic‐relevant behavioral phenotypes of a mouse model of cyclin‐dependent kinase‐like 5 deficiency disorder
Nicola Mottolese, Oceane Coiffard, Celeste Ferraguto, Athanasios Manolis, Elisabetta Ciani, Susanna Pietropaolo
Autism Research. 2024-09-05
10.1002/aur.3226

Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome
Celeste Ferraguto, Marion Piquemal-Lagoueillat, Valerie Lemaire, Maïté M. Moreau, Stefania Trazzi, Beatrice Uguagliati, Elisabetta Ciani, Sandrine S. Bertrand, Eric Louette, Bruno Bontempi, Susanna Pietropaolo
Neuropsychopharmacol.. 2024-09-02
10.1038/s41386-024-01956-6

Early Administration of the Phytocannabinoid Cannabidivarin Prevents the Neurobehavioral Abnormalities Associated with the Fmr1-KO Mouse Model of Fragile X Syndrome
Marika Premoli, William Fyke, Luigi Bellocchio, Valerie Lemaire, Marie Wolley-Roberts, Bruno Bontempi, Susanna Pietropaolo
Cells. 2023-07-25
10.3390/cells12151927

Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels
Celeste Ferraguto, Yohan Bouleau, Thibault Peineau, Didier Dulon, Susanna Pietropaolo
IJMS. 2023-07-24
10.3390/ijms241411863

The Impact of Mild Chronic Stress and Maternal Experience in the Fmr1 Mouse Model of Fragile X Syndrome
Enejda Subashi, Valerie Lemaire, Valeria Petroni, Susanna Pietropaolo
IJMS. 2023-07-13
10.3390/ijms241411398

Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications
Marika Premoli, Susanna Pietropaolo, Markus Wöhr, Nicola Simola, Sara Anna Bonini
Eur J of Neuroscience. 2023-03-26
10.1111/ejn.15957

Early Neurobehavioral Characterization of the CD Mouse Model of Williams–Beuren Syndrome
Silvia Giannoccaro, Celeste Ferraguto, Valeria Petroni, Coline Marcelly, Xavier Nogues, Victoria Campuzano, Susanna Pietropaolo
Cells. 2023-01-21
10.3390/cells12030391

Long-term behavioral effects of prenatal stress in the Fmr1-knock-out mouse model for fragile X syndrome
Valeria Petroni, Enejda Subashi, Marika Premoli, Maurizio Memo, Valerie Lemaire, Susanna Pietropaolo
Front. Cell. Neurosci.. 2022-10-27
10.3389/fncel.2022.917183

Editorial: Acoustic communication analysis for understanding animal behavior
Sara Anna Bonini, Susanna Pietropaolo
Front. Behav. Neurosci.. 2022-08-03
10.3389/fnbeh.2022.991573

Ultrasonic Vocalizations in Adult C57BL/6J Mice: The Role of Sex Differences and Repeated Testing
Marika Premoli, Valeria Petroni, Ronald Bulthuis, Sara Anna Bonini, Susanna Pietropaolo
Front. Behav. Neurosci.. 2022-07-14
10.3389/fnbeh.2022.883353

Editorial: Targeting Excitation-Inhibition Imbalance in Neurodevelopmental and Autism Spectrum Disorders
Susanna Pietropaolo, Giovanni Provenzano
Front. Neurosci.. 2022-07-08
10.3389/fnins.2022.968115

Scribble Controls Social Motivation Behavior through the Regulation of the ERK/Mnk1 Pathway
Maïté M. Moreau, Susanna Pietropaolo, Jérôme Ezan, Benjamin J. A. Robert, Sylvain Miraux, Marlène Maître, Yoon Cho, Wim E. Crusio, Mireille Montcouquiol, Nathalie Sans
Cells. 2022-05-10
10.3390/cells11101601

Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene-environment interactions.
Valeria Petroni, Enejda Subashi, Marika Premoli, Markus Wöhr, Wim E. Crusio, Valerie Lemaire, Susanna Pietropaolo
Sci Rep. 2022-05-04
10.1038/s41598-022-11083-1

The role of the endocannabinoid system as a therapeutic target for autism spectrum disorder: Lessons from behavioral studies on mouse models
Susanna Pietropaolo, Giovanni Marsicano
Neuroscience & Biobehavioral Reviews. 2022-01-01
10.1016/j.neubiorev.2021.11.031

Biotechnologies and Animals: The Impact of Genetic Engineering on Human-Animal Relationships
Susanna Pietropaolo
The Palgrave Macmillan Animal Ethics Series. 2022-01-01
10.1007/978-3-030-85277-1_12

Communication and social interaction in the cannabinoid‐type 1 receptor null mouse: Implications for autism spectrum disorder
William Fyke, Marika Premoli, Victor Echeverry Alzate, José A. López‐Moreno, Valerie Lemaire‐Mayo, Wim E. Crusio, Giovanni Marsicano, Markus Wöhr, Susanna Pietropaolo
Autism Research. 2021-06-26
10.1002/aur.2562

The role of the endocannabinoid system in autism spectrum disorders: Evidence from mouse studies.
Susanna Pietropaolo, Luigi Bellocchio, Inés Bouzón-Arnáiz, Benjamin K. Yee
Progress in Molecular Biology and Translational Science. 2020-01-01
10.1016/bs.pmbts.2020.04.016

Potential Involvement of Impaired BKCa Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome.
Maria Isabel Carreno-Munoz, Fabienne Martins, Maria Carmen Medrano, Elisabetta Aloisi, Susanna Pietropaolo, Corentin Dechaud, Enejda Subashi, Guillaume Bony, Melanie Ginger, Abdelmalik Moujahid, Andreas Frick, Xavier Leinekugel
Neuropsychopharmacology. 2017-07-19
10.1038/npp.2017.149

Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases
Julie Gaudissard, Melanie Ginger, Marika Premoli, Maurizio Memo, Andreas Frick, Susanna Pietropaolo
Autism Research. 2017-06-07
10.1002/aur.1814

Behavioral effects of chronic stress in the Fmr1 mouse model for fragile X syndrome.
Valerie Lemaire-Mayo, Enejda Subashi, Nadia Henkous, Daniel Beracochea, Susanna Pietropaolo
Behavioural Brain Research. 2017-03-01
10.1016/j.bbr.2016.11.051

Omics analysis of mouse brain models of human diseases.
Véronique Paban, Béatrice Loriod, Claude Villard, Luc Buee, David Blum, Susanna Pietropaolo, Yoon H. Cho, Sylvie Gory-Faure, Elodie Mansour, Ali Gharbi, Béatrice Alescio-Lautier
Gene. 2017-02-01
10.1016/j.gene.2016.11.022

Gene-Environment Interactions in Neurodevelopmental Disorders
Susanna Pietropaolo, Wim E. Crusio, Joram Feldon
Neural Plasticity. 2017-01-01
10.1155/2017/9272804

Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington's disease.
Alienor Ragot, Susanna Pietropaolo, Jean Vincent, Pauline Delage, Hongyu Zhang, Bernadette Allinquant, Xavier Leinekugel, André Fischer, Yoon H. Cho
Brain Behav. 2015-06-24
10.1002/brb3.361

Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington's Disease Mice.
Fanny Lebreton, Sebastien Cayzac, Susanna Pietropaolo, Yannick Jeantet, Yoon H. Cho
PLoS ONE. 2015-05-12
10.1371/journal.pone.0126972

Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington's disease.
Susanna Pietropaolo, Luigi Bellocchio, Andrea Ruiz-Calvo, Magali Cabanas, Zhuowei Du, Manuel Guzmán, Maurice Garret, Yoon H. Cho
Neuropharmacology. 2015-02-01
10.1016/j.neuropharm.2014.07.021

Treatment Approaches in Rodent Models for Autism Spectrum Disorder.
Susanna Pietropaolo, Wim E. Crusio, Francesca R. D’amato
Social Behavior from Rodents to Humans. 2015-01-01
10.1007/7854_2015_433

Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice.
Yu Zhang, Audrey Bonnan, Guillaume Bony, Isabelle Ferezou, Susanna Pietropaolo, Melanie Ginger, Nathalie Sans, Jean Rossier, Ben Oostra, Gwen LeMasson, Andreas Frick
Nat Neurosci. 2014-11-10
10.1038/nn.3864

Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice
Susanna Pietropaolo, Mena Goubran, Corinne Joffre, Agnes Aubert, Valerie Lemaire-Mayo, Wim E. Crusio, Sophie Layé
Psychoneuroendocrinology. 2014-11-01
10.1016/j.psyneuen.2014.07.002

Early Social Enrichment Rescues Adult Behavioral and Brain Abnormalities in a Mouse Model of Fragile X Syndrome
Diego Oddi, Enejda Subashi, Silvia Middei, Luigi Bellocchio, Valerie Lemaire-Mayo, Manuel Guzmán, Wim E Crusio, Francesca R D'Amato, Susanna Pietropaolo
Neuropsychopharmacol. 2014-10-28
10.1038/npp.2014.291

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule
Betty Hébert, Susanna Pietropaolo, Sandra Même, Béatrice Laudier, Anthony Laugeray, Nicolas Doisne, Angélique Quartier, Sandrine Lefeuvre, Laurence Got, Dominique Cahard, Frédéric Laumonnier, Wim E Crusio, Jacques Pichon, Arnaud Menuet, Olivier Perche, Sylvain Briault
Orphanet J Rare Dis. 2014-08-01
10.1186/s13023-014-0124-6

Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule
Betty Hébert, Susanna Pietropaolo, Sandra Même, Béatrice Laudier, Anthony Laugeray, Nicolas Doisne, Angélique Quartier, Sandrine Lefeuvre, Laurence Got, Dominique Cahard, Frédéric Laumonnier, Wim E Crusio, Jacques Pichon, Arnaud Menuet, Olivier Perche, Sylvain Briault
Orphanet J Rare Dis. 2014-08-01
10.1186/S13023-014-0124-6

Environmental enrichment eliminates the anxiety phenotypes in a triple transgenic mouse model of Alzheimer's disease.
Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee
Cogn Affect Behav Neurosci. 2014-02-04
10.3758/s13415-014-0253-3

Monogenic mouse models of social dysfunction: Implications for autism
D. Oddi, W.E. Crusio, F.R. D’Amato, S. Pietropaolo
Behavioural Brain Research. 2013-08-01
10.1016/j.bbr.2013.01.002

Early development of social deficits in APP and APP-PS1 mice
Susanna Pietropaolo, Pauline Delage, Fanny Lebreton, Wim E. Crusio, Yoon H. Cho
Neurobiology of Aging. 2012-05-01
10.1016/j.neurobiolaging.2011.09.012

Sex-dependent changes in social behaviors in motor pre-symptomatic R6/1 mice
Susanna Pietropaolo, Pauline Delage, Sebastien Cayzac, Wim E. Crusio, Yoon H. Cho
PLoS ONE. 2011-05-16
10.1371/journal.pone.0019965

Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice
Susanna Pietropaolo, Aurélie Guilleminot, Benoît Martin, Francesca R. D'Amato, Wim E. Crusio
PLoS ONE. 2011-02-22
10.1371/journal.pone.0017073

Strain-dependent changes in acoustic startle response and its plasticity across adolescence in Mice
Susanna Pietropaolo, Wim E. Crusio
Behav Genet. 2009-07-30
10.1007/s10519-009-9291-y

Age-related accumulation of Reelin in amyloid-like deposits
Irene Knuesel, Myriel Nyffeler, Cecile Mormède, Mary Muhia, Urs Meyer, Susanna Pietropaolo, Benjamin K. Yee, Christopher R. Pryce, Frank M. LaFerla, Aline Marighetto, Joram Feldon
Neurobiology of Aging. 2009-05-01
10.1016/j.neurobiolaging.2007.08.011

Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic mouse model.
Susanna Pietropaolo, Yan Sun, Ruixi Li, Corinne Brana, Joram Feldon, Benjamin K. Yee
Behavioral Neuroscience. 2009-01-01
10.1037/a0013607

The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective.
Susanna Pietropaolo, Yan Sun, Ruixi Li, Corinne Brana, Joram Feldon, Benjamin K. Yee
Behavioural Brain Research. 2008-09-01
10.1016/j.bbr.2008.03.014

The postweaning social isolation in C57BL/6 mice: preferential vulnerability in the male sex.
Susanna Pietropaolo, Philipp Singer, Joram Feldon, Benjamin K. Yee
Psychopharmacology. 2008-03-04
10.1007/s00213-008-1081-3

Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.
Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee
Behavioral Neuroscience. 2008-01-01
10.1037/a0012520

Nonphysical contact between cagemates alleviates the social isolation syndrome in C57BL/6 male mice.
Susanna Pietropaolo, Joram Feldon, Benjamin K. Yee
Behavioral Neuroscience. 2008-01-01
10.1037/0735-7044.122.3.505

Bidirectional changes in water-maze learning following recombinant adenovirus-associated viral vector (rAAV)-mediated brain-derived neurotrophic factor expression in the rat hippocampus.
Susanna Pietropaolo, Jean-Charles Paterna, Hansruedi Büeler, Joram Feldon, Benjamin K. Yee
Behavioural Pharmacology. 2007-09-01
10.1097/fbp.0b013e3282da0bf6

The behavioral sequela following the prevention of home-cage grid-climbing activity in C57BL/6 mice.
Susanna Pietropaolo, Matti Mintz, Joram Feldon, Benjamin K. Yee
Behavioral Neuroscience. 2007-01-01
10.1037/0735-7044.121.2.345

The expression of prepulse inhibition of the acoustic startle reflex as a function of three pulse stimulus intensities, three prepulse stimulus intensities, and three levels of startle responsiveness in C57BL6/J mice.
Benjamin K. Yee, Tilly Chang, Susanna Pietropaolo, Joram Feldon
Behavioural Brain Research. 2005-09-01
10.1016/j.bbr.2005.05.013

Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment.
S PIETROPAOLO, I BRANCHI, F CIRULLI, F CHIAROTTI, L ALOE, E ALLEVA
Physiology & Behavior. 2004-05-01
10.1016/j.physbeh.2004.02.022