Central respiratory command and microglia: An early-life partnership
Muriel Thoby-Brisson
Current Opinion in Neurobiology. 2023-10-01
10.1016/j.conb.2023.102756

Microglia shape the embryonic development of mammalian respiratory networks
Marie-Jeanne Cabirol, Laura Cardoit, Gilles Courtand, Marie-Eve Mayeur, John Simmers, Olivier Pascual, Muriel Thoby-Brisson
eLife. 2022-11-02
10.7554/eLife.80352

Perinatal development of central vestibular neurons in mice.
Christophe J. Dubois, Laura Cardoit, John Simmers, François M. Lambert, Muriel Thoby-Brisson
Front. Neurosci.. 2022-09-01
10.3389/fnins.2022.935166

Chronic maternal exposure to titanium dioxide nanoparticles alters breathing in newborn offspring
Eloïse Colnot, Laura Cardoit, Marie-Jeanne Cabirol, Lydia Roudier, Marie-Helene Delville, Anne Fayoux, Muriel Thoby-Brisson, Laurent Juvin, Didier Morin
Part Fibre Toxicol. 2022-08-18
10.1186/s12989-022-00497-4

Neurogenic mechanisms for locomotor-respiratory coordination in mammals
Laurent Juvin, Eloïse Colnot, Grégory Barrière, Muriel Thoby-Brisson, Didier Morin
Front. Neuroanat.. 2022-07-28
10.3389/fnana.2022.953746

Obstructive Apneas in a Mouse Model of Congenital Central Hypoventilation Syndrome
Amélia Madani, Gabriel Pitollat, Eléonore Sizun, Laura Cardoit, Maud Ringot, Thomas Bourgeois, Nelina Ramanantsoa, Christophe Delclaux, Stéphane Dauger, Marie-Pia d’Ortho, Muriel Thoby-Brisson, Jorge Gallego, Boris Matrot
Am J Respir Crit Care Med. 2021-11-15
10.1164/rccm.202104-0887oc

Synergistic interaction between sensory inputs and propriospinal signaling underlying quadrupedal locomotion
Marie Boulain, Ines Khsime, Mélissa Sourioux, Muriel Thoby‐Brisson, Grégory Barrière, John Simmers, Didier Morin, Laurent Juvin
J Physiol. 2021-08-19
10.1113/JP281861

A Rodent Model of Mild Neonatal Hypoxic Ischemic Encephalopathy
Julien Gotchac, Laura Cardoit, Muriel Thoby-Brisson, Olivier Brissaud
Front. Neurol.. 2021-05-05
10.3389/fneur.2021.637947

Modulation of respiratory network activity by forelimb and hindlimb locomotor generators
Jean‐Patrick Le Gal, Eloïse Colnot, Laura Cardoit, Julien Bacqué Cazenave, Muriel Thoby‐Brisson, Laurent Juvin, Didier Morin
Eur J Neurosci. 2020-03-09
10.1111/ejn.14717

Neural mechanisms for sigh generation during prenatal development
Muriel Thoby-Brisson
Journal of Neurophysiology. 2018-09-01
10.1152/jn.00314.2018

Acute exposure to zinc oxide nanoparticles critically disrupts operation of the respiratory neural network in neonatal rat.
Nicolosi A, Cardoit L, Pasquereau P, Jaillet C, Thoby-Brisson M, Juvin L, Morin D
NeuroToxicology. 2018-07
10.1016/j.neuro.2018.05.006

Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus
Francois M Lambert, Laura Cardoit, Elric Courty, Marion Bougerol, Muriel Thoby-Brisson, John Simmers, Hervé Tostivint, Didier Le Ray
eLife. 2018-05-30
10.7554/eLife.30693

Role of the K+-Cl– Cotransporter KCC2a Isoform in Mammalian Respiration at Birth
Christophe J. Dubois, Laura Cardoit, Veronika Schwarz, Marika Markkanen, Matti S. Airaksinen, Pavel Uvarov, John Simmers, Muriel Thoby-Brisson
eNeuro. 2018-01-01
10.1523/ENEURO.0264-18.2018

The embryonic development of hindbrain respiratory networks is unaffected by mutation of the planar polarity protein Scribble.
Marc Chevalier, Laura Cardoit, Maïté Moreau, Nathalie Sans, Mireille Montcouquiol, John Simmers, Muriel Thoby-Brisson
Neuroscience. 2017-08-01
10.1016/j.neuroscience.2017.05.046

Development of pacemaker properties and rhythmogenic mechanisms in the mouse embryonic respiratory network
Marc Chevalier, Natalia Toporikova, John Simmers, Muriel Thoby-Brisson
eLife. 2016-07-19
10.7554/eLife.16125

Mechanisms Underlying Adaptation of Respiratory Network Activity to Modulatory Stimuli in the Mouse Embryo
Marc Chevalier, Rafaël De Sa, Laura Cardoit, Muriel Thoby-Brisson
Neural Plasticity. 2016-01-01
10.1155/2016/3905257

Sigh and Eupnea Rhythmogenesis Involve Distinct Interconnected Subpopulations: A Combined Computational and Experimental Study
Natalia Toporikova, Marc Chevalier, Muriel Thoby-Brisson
eneuro. 2015-03-01
10.1523/eneuro.0074-14.2015

Generation of BAC transgenic tadpoles enabling live imaging of motoneurons by using the urotensin II-related peptide (ust2b) gene as a driver.
Marion Bougerol, Frédéric Auradé, François M. Lambert, Didier Le Ray, Denis Combes, Muriel Thoby-Brisson, Frédéric Relaix, Nicolas Pollet, Hervé Tostivint
PLoS ONE. 2015-02-06
10.1371/journal.pone.0117370

Emergence of sigh rhythmogenesis in the embryonic mouse
Coralie Chapuis, Sandra Autran, Gilles Fortin, John Simmers, Muriel Thoby‐Brisson
J Physiol. 2014-03-21
10.1113/jphysiol.2013.268730

Remote Control of Respiratory Neural Network by Spinal Locomotor Generators
Jean-Patrick Le Gal, Laurent Juvin, Laura Cardoit, Muriel Thoby-Brisson, Didier Morin
PLoS ONE. 2014-02-20
10.1371/journal.pone.0089670

Respiratory circuits: development, function and models
Nicholas M Mellen, Muriel Thoby-Brisson
Current Opinion in Neurobiology. 2012-08-01
10.1016/j.conb.2012.01.001

Brainstem Respiratory Oscillators Develop Independently of Neuronal Migration Defects in the Wnt/PCP Mouse Mutant looptail
Muriel Thoby-Brisson, Julien Bouvier, Derrick M. Glasco, Michelle E. Stewart, Charlotte Dean, Jennifer N. Murdoch, Jean Champagnat, Gilles Fortin, Anand Chandrasekhar
PLoS ONE. 2012-02-17
10.1371/journal.pone.0031140

Breathing without CO2 Chemosensitivity in Conditional Phox2b Mutants
N. Ramanantsoa, M.-R. Hirsch, M. Thoby-Brisson, V. Dubreuil, J. Bouvier, P.-L. Ruffault, B. Matrot, G. Fortin, J.-F. Brunet, J. Gallego, C. Goridis
Journal of Neuroscience. 2011-09-07
10.1523/jneurosci.1721-11.2011

Prenatal development of central rhythm generation
Jean Champagnat, Marie-Pierre Morin-Surun, Julien Bouvier, Muriel Thoby-Brisson, Gilles Fortin
Respiratory Physiology & Neurobiology. 2011-08-01
10.1016/j.resp.2011.04.013

Phox2b, congenital central hypoventilation syndrome and the control of respiration.
Christo Goridis, Véronique Dubreuil, Muriel Thoby-Brisson, Gilles Fortin, Jean-François Brunet
Seminars in Cell & Developmental Biology. 2010-10-01
10.1016/j.semcdb.2010.07.006

Hindbrain interneurons and axon guidance signaling critical for breathing.
Julien Bouvier, Muriel Thoby-Brisson, Nicolas Renier, Véronique Dubreuil, Johan Ericson, Jean Champagnat, Alessandra Pierani, Alain Chédotal, Gilles Fortin
Nat Neurosci. 2010-08-02
10.1038/nn.2622

Teashirt 3 Regulates Development of Neurons Involved in Both Respiratory Rhythm and Airflow Control
X. Caubit, M. Thoby-Brisson, N. Voituron, P. Filippi, M. Bevengut, H. Faralli, S. Zanella, G. Fortin, G. Hilaire, L. Fasano
Journal of Neuroscience. 2010-07-14
10.1523/jneurosci.1765-10.2010

Genetic factors determining the functional organization of neural circuits controlling rhythmic movements
J. Champagnat, M. Thoby-Brisson, G. Fortin
Breathe, Walk and Chew: The Neural Challenge: Part I. 2010-01-01
10.1016/b978-0-444-53613-6.00003-4

Defective Respiratory Rhythmogenesis and Loss of Central Chemosensitivity in Phox2b Mutants Targeting Retrotrapezoid Nucleus Neurons
V. Dubreuil, M. Thoby-Brisson, M. Rallu, K. Persson, A. Pattyn, C. Birchmeier, J.-F. Brunet, G. Fortin, C. Goridis
Journal of Neuroscience. 2009-11-25
10.1523/jneurosci.2623-09.2009

Developmental basis of the rostro-caudal organization of the brainstem respiratory rhythm generator
J. Champagnat, M. P. Morin-Surun, G. Fortin, M. Thoby-Brisson
Phil. Trans. R. Soc. B. 2009-09-12
10.1098/rstb.2009.0090

Embryonic emergence of the respiratory rhythm generator
Gilles Fortin, Muriel Thoby-Brisson
Respiratory Physiology & Neurobiology. 2009-08-01
10.1016/j.resp.2009.06.013

Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex
Muriel Thoby-Brisson, Mattias Karlén, Ning Wu, Patrick Charnay, Jean Champagnat, Gilles Fortin
Nat Neurosci. 2009-07-05
10.1038/nn.2354

Brain-derived neurotrophic factor enhances fetal respiratory rhythm frequency in the mouse preBötzinger complexin vitro
Julien Bouvier, Sandra Autran, Nathalie Dehorter, David M. Katz, Jean Champagnat, Gilles Fortin, Muriel Thoby-Brisson
European Journal of Neuroscience. 2008-08-01
10.1111/j.1460-9568.2008.06345.x

Differential Modulation of Neural Network and Pacemaker Activity Underlying Eupnea and Sigh-Breathing Activities
Andrew K. Tryba, Fernando Peña, Steven P. Lieske, Jean-Charles Viemari, Muriel Thoby-Brisson, Jan-Marino Ramirez
Journal of Neurophysiology. 2008-05-01
10.1152/jn.01192.2007

Anatomical and functional development of the pre-Bötzinger complex in prenatal rodents
Muriel Thoby-Brisson, John J. Greer
Journal of Applied Physiology. 2008-04-01
10.1152/japplphysiol.01061.2007

Abnormal inspiratory depth in Phox2a haploinsufficient mice
L.J. Wrobel, M. Ogier, F. Chatonnet, S. Autran, V. Mézières, M. Thoby-Brisson, H. McLean, C. Taeron, J. Champagnat
Neuroscience. 2007-03-01
10.1016/j.neuroscience.2006.11.055

Vesicular Glutamate Transporter 2 Is Required for Central Respiratory Rhythm Generation But Not for Locomotor Central Pattern Generation
A. Wallen-Mackenzie, H. Gezelius, M. Thoby-Brisson, A. Nygard, A. Enjin, F. Fujiyama, G. Fortin, K. Kullander
Journal of Neuroscience. 2006-11-22
10.1523/jneurosci.3855-06.2006

Acute role of the brain-derived neurotrophic factor (BDNF) on the respiratory neural network activity in mice in vitro
Julien Bouvier, Sandra Autran, Gilles Fortin, Jean Champagnat, Muriel Thoby-Brisson
Journal of Physiology-Paris. 2006-11-01
10.1016/j.jphysparis.2007.05.008

Ontogeny of central rhythm generation in chicks and rodents
F. Chatonnet, C. Borday, L. Wrobel, M. Thoby-Brisson, G. Fortin, H. McLean, J. Champagnat
Respiratory Physiology & Neurobiology. 2006-11-01
10.1016/j.resp.2006.02.004

The pre-Bötzinger oscillator in the mouse embryo
C. Borday, C. Vias, S. Autran, M. Thoby-Brisson, J. Champagnat, G. Fortin
Journal of Physiology-Paris. 2006-11-01
10.1016/j.jphysparis.2007.05.007

Mice Lacking Brain/Kidney Phosphate-Activated Glutaminase Have Impaired Glutamatergic Synaptic Transmission, Altered Breathing, Disorganized Goal-Directed Behavior and Die Shortly after Birth
J. Masson
Journal of Neuroscience. 2006-04-26
10.1523/jneurosci.4241-05.2006

Neural tube patterning by Krox20 and emergence of a respiratory control
C. Borday, F. Chatonnet, M. Thoby-Brisson, J. Champagnat, G. Fortin
Respiratory Physiology & Neurobiology. 2005-11-01
10.1016/j.resp.2005.02.014

Emergence of the Pre-Botzinger Respiratory Rhythm Generator in the Mouse Embryo
M. Thoby-Brisson
Journal of Neuroscience. 2005-04-27
10.1523/jneurosci.0551-05.2005

Developmental gene control of brainstem function: views from the embryo
Caroline Borday, Ludovic Wrobel, Gilles Fortin, Jean Champagnat, Christelle Thaëron-Antôno, Muriel Thoby-Brisson
Progress in Biophysics and Molecular Biology. 2004-02-01
10.1016/j.pbiomolbio.2003.11.002

BDNF Preferentially Targets Membrane Properties of Rhythmically Active Neurons in the pre-Bötzinger Complex in Neonatal Mice
Muriel Thoby-Brisson, Sandra Autran, Gilles Fortin, Jean Champagnat
Advances in Experimental Medicine and Biology. 2004-01-01
10.1007/0-387-27023-x_18

Expression of Functional Tyrosine Kinase B Receptors by Rhythmically Active Respiratory Neurons in the Pre-Bötzinger Complex of Neonatal Mice
Muriel Thoby-Brisson, Bruno Cauli, Jean Champagnat, Gilles Fortin, David M. Katz
J. Neurosci.. 2003-08-20
10.1523/jneurosci.23-20-07685.2003

Developmental molecular switches regulating breathing patterns in CNS
Caroline Borday, Véronique Abadie, Fabrice Chatonnet, Muriel Thoby-Brisson, Jean Champagnat, Gilles Fortin
Respiratory Physiology & Neurobiology. 2003-05-01
10.1016/s1569-9048(03)00031-4

Emergence of neural net function during brain development
Jean Champagnat, Monique Denavit-Saubié, Gilles Fortin, Arthur S. Foutz, Christelle Antono-Thaëron, Muriel Thoby-Brisson
Journal of Physiology-Paris. 2003-01-01
10.1016/j.jphysparis.2003.10.001

From Hindbrain Segmentation to Breathing After Birth: Developmental Patterning in Rhombomeres 3 and 4
Fabrice Chatonnet, Eduardo Domínguez del Toro, Muriel Thoby-Brisson, Jean Champagnat, Gilles Fortin, Filippo M. Rijli, Christelle Thaëron-Antôno
MN. 2003-01-01
10.1385/mn:28:3:277

Long-Term Neuromodulatory Regulation of a Motor Pattern–Generating Network: Maintenance of Synaptic Efficacy and Oscillatory Properties
Muriel Thoby-Brisson, John Simmers
Journal of Neurophysiology. 2002-12-01
10.1152/jn.00482.2001

Early development of respiratory rhythm generation in mouse and chick
Fabrice Chatonnet, Muriel Thoby-Brisson, Véronique Abadie, Eduardo Domı́nguez del Toro, Jean Champagnat, Gilles Fortin
Respiratory Physiology & Neurobiology. 2002-07-01
10.1016/s1569-9048(02)00033-2

Identification of Two Types of Inspiratory Pacemaker Neurons in the Isolated Respiratory Neural Network of Mice
Muriel Thoby-Brisson, Jan-Marino Ramirez
Journal of Neurophysiology. 2001-07-01
10.1152/jn.2001.86.1.104

Reconfiguration of the Central Respiratory Network Under Normoxic and Hypdxic Conditions
Steven P. Lieske, Muriel Thoby-Brisson, Jan-Marino Ramirez
Advances in Experimental Medicine and Biology. 2001-01-01
10.1007/978-1-4615-1375-9_27

Role of Inspiratory Pacemaker Neurons in Mediating the Hypoxic Response of the Respiratory NetworkIn Vitro
Muriel Thoby-Brisson, Jan-Marino Ramirez
J. Neurosci.. 2000-08-01
10.1523/jneurosci.20-15-05858.2000

Transition to Endogenous Bursting After Long-Term Decentralization Requires De Novo Transcription in a Critical Time Window
Muriel Thoby-Brisson, John Simmers
Journal of Neurophysiology. 2000-07-01
10.1152/jn.2000.84.1.596

Reconfiguration of the neural network controlling multiple breathing patterns: eupnea, sighs and gasps
S. P. Lieske, M. Thoby-Brisson, P. Telgkamp, J. M. Ramirez
Nat Neurosci. 2000-06-01
10.1038/75776

The Role of the Hyperpolarization-Activated Current in Modulating Rhythmic Activity in the Isolated Respiratory Network of Mice
Muriel Thoby-Brisson, Petra Telgkamp, Jan-Marino Ramirez
J. Neurosci.. 2000-04-15
10.1523/jneurosci.20-08-02994.2000

Neuromodulatory Inputs Maintain Expression of a Lobster Motor Pattern-Generating Network in a Modulation-Dependent State: Evidence from Long-Term DecentralizationIn Vitro
Muriel Thoby-Brisson, John Simmers
J. Neurosci.. 1998-03-15
10.1523/jneurosci.18-06-02212.1998