Jean-Luc Morel

Équipe : Motoneurons and synaptic partners (MotoPSyn)
Chercheur  |  CR  |  CNRS


Publications

Physical exercise restores adult neurogenesis deficits induced by simulated microgravity
Alexandra Gros, Fandilla Marie Furlan, Vanessa Rouglan, Alexandre Favereaux, Bruno Bontempi, Jean-Luc Morel
npj Microgravity volume. 2024-06-21

10.1038/s41526-024-00411-6

Hypergravity Increases Blood–Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice
David Dubayle, Arnaud Vanden-Bossche, Tom Peixoto, Jean-Luc Morel
Cells. 2023-02-24

10.3390/cells12050734

Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes
Jean-Luc Morel, Nathalie Mokrzycki, Guy Lippens, Hervé Drobecq, Pierre Sautière, Michel Hugues
Toxins. 2022-11-10

10.3390/toxins14110780

Simulated Microgravity Subtlety Changes Monoamine Function across the Rat Brain
Alexandra Gros, Léandre Lavenu, Jean-Luc Morel, Philippe De Deurwaerdère
IJMS. 2021-10-29

10.3390/ijms222111759

Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis
Florian Gueniot, Sebastien Rubin, Pauline Bougaran, Alice Abelanet, Jean Luc Morel, Bruno Bontempi, Carole Proust, Pascale Dufourcq, Thierry Couffinhal, Cecile Duplàa
J Cereb Blood Flow Metab. 2021-10-13

10.1177/0271678X211048981

Effects of centrifugation and whole-body vibrations on blood–brain barrier permeability in mice
David Dubayle, Arnaud Vanden-Bossche, Mathieu Beraneck, Laurence Vico, Jean-Luc Morel
npj Microgravity. 2020-01-07

10.1038/s41526-019-0094-z

Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells
Lamia Azzi-Martin, Wencan He, Christelle Péré-Védrenne, Victoria Korolik, Chloé Alix, Martina Prochazkova-Carlotti, Jean-Luc Morel, Emilie Le Roux-Goglin, Philippe Lehours, Mojgan Djavaheri-Mergny, Christophe F. Grosset, Christine Varon, Pierre Dubus, Armelle Ménard
PLoS Pathog. 2019-09-30

10.1371/journal.ppat.1007921

Presenilin 1 mutation decreases both calcium and contractile responses in cerebral arteries
Xavier Toussay, Jean-Luc Morel, Nathalie Biendon, Lolita Rotureau, François-Pierre Legeron, Marie-Charlotte Boutonnet, Yoon H. Cho, Nathalie Macrez
Neurobiology of Aging. 2017-10-01

10.1016/j.neurobiolaging.2017.06.015

Changes in C57BL6 mouse hippocampal transcriptome induced by hypergravity mimic acute corticosterone-induced stress
Alice Pulga, Yves Porte, Jean-Luc Morel
Front. Mol. Neurosci.. 2016-12-26

10.3389/fnmol.2016.00153

TRPP2 modulates ryanodine- and inositol-1,4,5-trisphosphate receptors-dependent Ca2+ signals in opposite ways in cerebral arteries
Azzedine Abdi, Claire Mazzocco, François-Pierre Légeron, Blaise Yvert, Nathalie Macrez, Jean-Luc Morel
Cell Calcium. 2015-11-01

10.1016/j.ceca.2015.07.003

Blood brain barrier precludes the cerebral arteries to intravenously-injected antisense oligonucleotide.
Raphael Boursereau, Arnaud Donadieu, Fabrice Dabertrand, David Dubayle, Jean-Luc Morel
European Journal of Pharmacology. 2015-01-01

10.1016/j.ejphar.2014.11.027

Up-regulation of ryanodine receptor expression increases the calcium-induced calcium release and spontaneous calcium signals in cerebral arteries from hindlimb unloaded rats
Jean-Luc Morel, Fabrice Dabertrand, Yves Porte, Anne Prevot, Nathalie Macrez
Pflugers Arch - Eur J Physiol. 2013-11-15

10.1007/s00424-013-1387-9

Effect of aging on calcium signaling in C57Bl6J mouse cerebral arteries
Carole Georgeon-Chartier, Céline Menguy, Anne Prévot, Jean-Luc Morel
Pflugers Arch - Eur J Physiol. 2012-12-14

10.1007/s00424-012-1195-7

The 22nd Ion Channel Meeting, September 2011, France
Jean-Marc Goaillard, Laurent Groc, Sabine Lévi, Massimo Mantegazza, Fabrice Matifat, Jean-Luc Morel, Anne Baron-Forster
Channels. 2012-05-01

10.4161/chan.20795

Spaceflight regulates ryanodine receptor subtype 1 in portal vein myocytes in the opposite way of hypertension
Fabrice Dabertrand, Yves Porte, Nathalie Macrez, Jean-Luc Morel
Journal of Applied Physiology. 2012-02-01

10.1152/japplphysiol.00733.2011

Learning on Jupiter, learning on the Moon: The dark side of the G-force. Effects of gravity changes on neurovascular unit and modulation of learning and memory
Yves Porte, Jean-Luc Morel
Front. Behav. Neurosci.. 2012-01-01

10.3389/fnbeh.2012.00064

Comparison between gentamycin and exon skipping treatments to restore ryanodine receptor subtype 2 functions in mdx mouse duodenum myocytes
Fabrice Dabertrand, Jean Mironneau, Morgana Henaff, Nathalie Macrez, Jean-Luc Morel
European Journal of Pharmacology. 2010-02-01

10.1016/j.ejphar.2009.11.034

The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice
Jean-Luc Morel, Fabrice Dabertrand, Nicolas Fritz, Morgana Henaff, Jean Mironneau, Nathalie Macrez
Journal of Cellular and Molecular Medicine. 2009-02-27

10.1111/j.1582-4934.2009.00718.x

Acetylcholine evokes an InsP3R1-dependent transient Ca 2+ signal in rat duodenum myocytes
Nicolas Fritz, Fabrice Dabertrand, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel
Can. J. Physiol. Pharmacol.. 2008-09-01

10.1139/Y08-067

Full length ryanodine receptor subtype 3 encodes spontaneous calcium oscillations in native duodenal smooth muscle cells
Fabrice Dabertrand, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel
Cell Calcium. 2008-08-01

10.1016/j.ceca.2007.11.009

Acetylcholine-induced Ca2+ oscillations are modulated by a Ca2+ regulation of InsP3R2 in rat portal vein myocytes
Nicolas Fritz, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel
Pflugers Arch - Eur J Physiol. 2007-11-20

10.1007/s00424-007-0379-z

RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle
N. Fritz, J.-L. Morel, L. H. Jeyakumar, S. Fleischer, P. D. Allen, J. Mironneau, N. Macrez
Journal of Cell Science. 2007-10-09

10.1242/jcs.009415

Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium
Fabrice Dabertrand, Nicolas Fritz, Jean Mironneau, Nathalie Macrez, Jean-Luc Morel
American Journal of Physiology-Cell Physiology. 2007-09-01

10.1152/ajpcell.00069.2007

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells
Fabrice Dabertrand, Jean-Luc Morel, Vincenzo Sorrentino, Jean Mironneau, Chantal Mironneau, Nathalie Macrez
Cell Calcium. 2006-07-01

10.1016/j.ceca.2006.03.008

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells
Fabrice Dabertrand, Jean-Luc Morel, Vincenzo Sorrentino, Jean Mironneau, Chantal Mironneau, Nathalie Macrez
Cell Calcium. 2006-07-01

10.1016/j.ceca.2006.03.008

Ryanodine receptor subtype 2 encodes Ca2+ oscillations activated by acetylcholine via the M2 muscarinic receptor/cADP-ribose signalling pathway in duodenum myocytes
N. Fritz
Journal of Cell Science. 2005-05-15

10.1242/jcs.02344

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes
Jean-Luc Morel, Lala Rakotoarisoa, Loice H. Jeyakumar, Sidney Fleischer, Chantal Mironneau, Jean Mironneau
J. Biol. Chem.. 2004-02-25

10.1074/jbc.M311124200

Crucial role of type 2 inositol 1,4,5-trisphosphate receptors for acetylcholine-induced Ca2+ oscillations in vascular myocytes
J.-L. Morel
Arteriosclerosis, Thrombosis, and Vascular Biology. 2003-09-01

10.1161/01.ATV.0000089013.82552.5D

Identification and function of ryanodine receptor subtype 3 in non-pregnant mouse myometrial cells
J. Mironneau, N. Macrez, J.L. Morel, V. Sorrentino, C. Mironneau
The Journal of Physiology. 2002-02-01

10.1113/jphysiol.2001.013046

Calcium signalling through nucleotide receptor P2X1 in rat portal vein myocytes
J. Mironneau, F. Coussin, J. L. Morel, C. Barbot, L. H. Jeyakumar, S. Fleischer, C. Mironneau
The Journal of Physiology. 2001-10-01

10.1111/j.1469-7793.2001.0339c.xd

Ca2+ signals mediated by Ins(1,4,5)P3-gated channels in rat ureteric myocytes
François-Xavier BOITTIN, Frédéric COUSSIN, Jean-Luc MOREL, Guillaume HALET, Nathalie MACREZ, Jean MIRONNEAU
Biochem. J.. 2000-07-01

10.1042/0264-6021:3490323

Requirement of ryanodine receptor subtypes 1 and 2 for Ca2+-induced Ca2+ release in vascular myocytes
Frédéric Coussin, Nathalie Macrez, Jean-Luc Morel, Jean Mironneau
J. Biol. Chem.. 2000-03-24

10.1074/jbc.275.13.9596

A βγ dimer derived from G13 transduces the angiotensin AT1 receptor signal to stimulation of Ca2+ channels in rat portal vein myocytes
Nathalie Macrez, Jean-Luc Morel, Frank Kalkbrenner, Patricia Viard, Günter Schultz, Jean Mironneau
J. Biol. Chem.. 1997-09-12

10.1074/jbc.272.37.23180

Specific G(q) protein involvement in muscarinic M3 receptor-induced phosphatidylinositol hydrolysis and Ca2+ release in mouse duodenal myocytes
J. L. Morel, N. Macrez, J. Mironneau
British Journal of Pharmacology. 1997-05-01

10.1038/sj.bjp.0701157

G protein heterotrimer Gα13β1γ3 couples the angiotensin AT(1A) receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes
Nathalie Macrez-Leprêtre, Frank Kalkbrenner, Jean-Luc Morel, Günter Schultz, Jean Mironneau
J. Biol. Chem.. 1997-04-11

10.1074/jbc.272.15.10095

Effects of phospholipase C inhibitors on Ca2+ channel stimulation and Ca2+ release from intracellular stores evoked by α1A- and α2A-adrenoceptors in rat portal vein myocytes
Nathalie Macrez-Leprêtre, Jean-Luc Morel, Jean Mironneau
Biochemical and Biophysical Research Communications. 1996-01-01

10.1006/bbrc.1996.0006

A Gi1-2-protein is required for α2A-adrenoceptor-induced stimulation of voltage-dependent Ca2+ channels in rat portal vein myocytes
Nathalie Macrez-Lepretre, Javier Ibarrondo, Serge Arnaudeau, Jean -Luc Morel, Gilles Guillon, Jean Mironneau
Pflugers Arch.. 1995-08-01

10.1007/BF00373897