GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice.
Irene B. Maroto, Carlos Costas-Insua, Carlos Montero-Fernández, Alba Hermoso-López, Margaux Lebouc, Raquel Bajo-Grañeras, Alicia Álvaro-Blázquez, Cristina Blázquez, Astrid Cannich, Giovanni Marsicano, Ricardo Martín, Jérôme Baufreton, Ignacio Rodríguez-Crespo, Luigi Bellocchio, Manuel Guzmán
J. Neurosci.. 2024-08-21
10.1523/jneurosci.0701-24.2024

Olfactory bulb astrocytes link social transmission of stress to cognitive adaptation in male mice
Paula Gómez-Sotres, Urszula Skupio, Tommaso Dalla Tor, Francisca Julio-Kalajzic, Astrid Cannich, Doriane Gisquet, Itziar Bonilla-Del Rio, Filippo Drago, Nagore Puente, Pedro Grandes, Luigi Bellocchio, Arnau Busquets-Garcia, Jaideep S. Bains, Giovanni Marsicano
Nat Commun. 2024-08-18
10.1038/s41467-024-51416-4

A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice.
Ignacio Fernández-Moncada, Gianluca Lavanco, Unai B. Fundazuri, Nasrin Bollmohr, Sarah Mountadem, Tommaso Dalla Tor, Pauline Hachaguer, Francisca Julio-Kalajzic, Doriane Gisquet, Roman Serrat, Luigi Bellocchio, Astrid Cannich, Bérénice Fortunato-Marsol, Yusuke Nasu, Robert E. Campbell, Filippo Drago, Carla Cannizzaro, Guillaume Ferreira, Anne-Karine Bouzier-Sore, Luc Pellerin, Juan P. Bolaños, Gilles Bonvento, L. Felipe Barros, Stephane H. R. Oliet, Aude Panatier, Giovanni Marsicano
Nat Commun. 2024-08-09
10.1038/s41467-024-51008-2

Single cell tracing of Pomc neurons reveals recruitment of ‘Ghost’ subtypes with atypical identity in a mouse model of obesity
Stéphane Leon, Vincent Simon, Thomas H. Lee, Lukas Steuernagel, Samantha Clark, Nasim Biglari, Thierry Lesté-Lasserre, Nathalie Dupuy, Astrid Cannich, Luigi Bellocchio, Philippe Zizzari, Camille Allard, Delphine Gonzales, Yves Le Feuvre, Emeline Lhuillier, Alexandre Brochard, Jean Charles Nicolas, Jérémie Teillon, Macha Nikolski, Giovanni Marsicano, Xavier Fioramonti, Jens C. Brüning, Daniela Cota, Carmelo Quarta
Nat Commun. 2024-04-24
10.1038/s41467-024-47877-2

Endogenous cannabinoids in the piriform cortex tune olfactory perception
Geoffrey Terral, Evan Harrell, Gabriel Lepousez, Yohan Wards, Dinghuang Huang, Tiphaine Dolique, Giulio Casali, Antoine Nissant, Pierre-Marie Lledo, Guillaume Ferreira, Giovanni Marsicano, Lisa Roux
Nat Commun. 2024-02-09
10.1038/s41467-024-45161-x

Striatopallidal cannabinoid type-1 receptors mediate amphetamine-induced sensitization
Yamuna Mariani, Ana Covelo, Rui S. Rodrigues, Francisca Julio-Kalajzić, Antonio C. Pagano Zottola, Gianluca Lavanco, Michela Fabrizio, Doriane Gisquet, Filippo Drago, Astrid Cannich, Jerome Baufreton, Giovanni Marsicano, Luigi Bellocchio
Current Biology. 2023-11-01
10.1016/j.cub.2023.09.075

An enquiry to the role of CB1 receptors in neurodegeneration.
Ignacio Fernández-Moncada, Abel Eraso-Pichot, Tommaso Dalla Tor, Bérénice Fortunato-Marsol, Giovanni Marsicano
Neurobiology of Disease. 2023-08-01
10.1016/j.nbd.2023.106235

Type‐1 cannabinoid receptors and their ever‐expanding roles in brain energy processes
Ignacio Fernández‐Moncada, Rui S. Rodrigues, Unai B. Fundazuri, Luigi Bellocchio, Giovanni Marsicano
Journal of Neurochemistry. 2023-07-28
10.1111/jnc.15922

Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials.
Margaret Haney, Monique Vallée, Sandy Fabre, Stephanie Collins Reed, Marion Zanese, Ghislaine Campistron, Caroline A. Arout, Richard W. Foltin, Ziva D. Cooper, Tonisha Kearney-Ramos, Mathilde Metna, Zuzana Justinova, Charles Schindler, Etienne Hebert-Chatelain, Luigi Bellocchio, Adeline Cathala, Andrea Bari, Roman Serrat, David B. Finlay, Filippo Caraci, Bastien Redon, Elena Martín-García, Arnau Busquets-Garcia, Isabelle Matias, Frances R. Levin, François-Xavier Felpin, Nicolas Simon, Daniela Cota, Umberto Spampinato, Rafael Maldonado, Yavin Shaham, Michelle Glass, Lars Lykke Thomsen, Helle Mengel, Giovanni Marsicano, Stéphanie Monlezun, Jean-Michel Revest, Pier Vincenzo Piazza
Nat Med. 2023-06-01
10.1038/s41591-023-02381-w

To deliberate, remember; to anticipate, forget: Cognitive deliberation profiles underpinning active forgetting-dependent everyday-like memory performance in young and aged mice
Christopher Stevens, Shaam Al Abed, Azza Sellami, Eva Ducourneau, Cathy Lacroix, Mathilde Bouchet, Faustine Roudier, Giovanni Marsicano, Aline Marighetto
. 2023-04-30
10.1101/2023.04.29.538679

Mitochondrial cannabinoid receptors gate corticosterone impact on novel object recognition
Urszula Skupio, Julia Welte, Roman Serrat, Abel Eraso-Pichot, Francisca Julio-Kalajzić, Doriane Gisquet, Astrid Cannich, Sebastien Delcasso, Isabelle Matias, Unai B. Fundazuri, Sandrine Pouvreau, Antonio C. Pagano Zottola, Gianluca Lavanco, Filippo Drago, Inigo Ruiz de Azua, Beat Lutz, Luigi Bellocchio, Arnau Busquets-Garcia, Francis Chaouloff, Giovanni Marsicano
Neuron. 2023-04-01
10.1016/j.neuron.2023.04.001

Age-dependent effects of estradiol on temporal memory: A role for the type 1 cannabinoid receptor?
Mylène Potier, Marlène Maitre, Thierry Leste-Lasserre, Giovanni Marsicano, Francis Chaouloff, Aline Marighetto
Psychoneuroendocrinology. 2023-02-01
10.1016/j.psyneuen.2022.106002

Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?
Ignacio Fernández-Moncada,Giovanni Marsicano
Essays in Biochemistry. 2023-01-16
10.1042/EBC20220089

Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis.
Joris Guyon, Ignacio Fernandez‐Moncada, Claire M Larrieu, Cyrielle L Bouchez, Antonio C Pagano Zottola, Johanna Galvis, Tiffanie Chouleur, Audrey Burban, Kevin Joseph, Vidhya M Ravi, Heidi Espedal, Gro Vatne Røsland, Boutaina Daher, Aurélien Barre, Benjamin Dartigues, Slim Karkar, Justine Rudewicz, Irati Romero‐Garmendia, Barbara Klink, Konrad Grützmann, Marie‐Alix Derieppe, Thibaut Molinié, Nina Obad, Céline Léon, Giorgio Seano, Hrvoje Miletic, Dieter Henrik Heiland, Giovanni Marsicano, Macha Nikolski, Rolf Bjerkvig, Andreas Bikfalvi, Thomas Daubon
EMBO Mol Med. 2022-10-24
10.15252/emmm.202115343

Expression of Functional Cannabinoid Type-1 (CB1) Receptor in Mitochondria of White Adipocytes
Antonio C. Pagano Zottola, Ilenia Severi, Astrid Cannich, Philippe Ciofi, Daniela Cota, Giovanni Marsicano, Antonio Giordano, Luigi Bellocchio
Cells. 2022-08-19
10.3390/cells11162582

Endocannabinoid signaling in astrocytes
Abel Eraso‐Pichot, Sandrine Pouvreau, Alexandre Olivera‐Pinto, Paula Gomez‐Sotres, Urszula Skupio, Giovanni Marsicano
Glia. 2022-07-13
10.1002/glia.24246

Metabolic Messengers: endocannabinoids
Arnau Busquets-García, Juan P. Bolaños, Giovanni Marsicano
Nat Metab. 2022-07-11
10.1038/s42255-022-00600-1

Imaging mitochondrial calcium dynamics in the central nervous system
Roman Serrat, Alexandre Oliveira-Pinto, Giovanni Marsicano, Sandrine Pouvreau
Journal of Neuroscience Methods. 2022-05-01
10.1016/j.jneumeth.2022.109560

Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model
Nadia Di Franco, Guillaume Drutel, Valérie Roullot-Lacarrière, Francisca Julio-Kalajzic, Valérie Lalanne, Agnès Grel, Thierry Leste-Lasserre, Isabelle Matias, Astrid Cannich, Delphine Gonzales, Vincent Simon, Daniela Cota, Giovanni Marsicano, Pier Vincenzo Piazza, Monique Vallée, Jean-Michel Revest
Molecular and Cellular Neuroscience. 2022-03-01
10.1016/j.mcn.2022.103705

Cannabinoid Signalling in the Brain: New Vistas
A. Busquets‐Garcia, M. Melis, L. Bellocchio, G. Marsicano
Eur J of Neuroscience. 2022-02-03
10.1111/ejn.15618

The role of the endocannabinoid system as a therapeutic target for autism spectrum disorder: Lessons from behavioral studies on mouse models
Susanna Pietropaolo, Giovanni Marsicano
Neuroscience & Biobehavioral Reviews. 2022-01-01
10.1016/j.neubiorev.2021.11.031

Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner
Julia De Meij, Zain Alfanek, Lydie Morel, Fanny Decoeur, Quentin Leyrolle, Katherine Picard, Micael Carrier, Agnes Aubert, Alexandra Séré, Céline Lucas, Gerald Laforest, Jean-Christophe Helbling, Marie-Eve Tremblay, Daniela Cota, Marie-Pierre Moisan, Giovanni Marsicano, Sophie Layé, Agnès Nadjar
Cannabis and Cannabinoid Research. 2021-12-01
10.1089/can.2020.0170

Astroglial ER-mitochondria calcium transfer mediates endocannabinoid-dependent synaptic integration
Roman Serrat, Ana Covelo, Vladimir Kouskoff, Sebastien Delcasso, Andrea Ruiz-Calvo, Nicolas Chenouard, Carol Stella, Corinne Blancard, Benedicte Salin, Francisca Julio-Kalajzić, Astrid Cannich, Federico Massa, Marjorie Varilh, Severine Deforges, Laurie M. Robin, Diego De Stefani, Arnau Busquets-Garcia, Frederic Gambino, Anna Beyeler, Sandrine Pouvreau, Giovanni Marsicano
Cell Reports. 2021-12-01
10.1016/j.celrep.2021.110133

Functional heterogeneity of POMC neurons relies on mTORC1 signaling
Nicolas Saucisse, Wilfrid Mazier, Vincent Simon, Elke Binder, Caterina Catania, Luigi Bellocchio, Roman A. Romanov, Stéphane Léon, Isabelle Matias, Philippe Zizzari, Carmelo Quarta, Astrid Cannich, Kana Meece, Delphine Gonzales, Samantha Clark, Julia M. Becker, Giles S.H. Yeo, Xavier Fioramonti, Florian T. Merkle, Sharon L. Wardlaw, Tibor Harkany, Federico Massa, Giovanni Marsicano, Daniela Cota
Cell Reports. 2021-10-01
10.1016/j.celrep.2021.109800

The temporal origin of dentate granule neurons dictates their role in spatial memory
Nuria Masachs, Vanessa Charrier, Fanny Farrugia, Valerie Lemaire, Nicolas Blin, Wilfrid Mazier, Sophie Tronel, Marie-Françoise Montaron, Shaoyu Ge, Giovanni Marsicano, Daniela Cota, Véronique Deroche-Gamonet, Cyril Herry, Djoher Nora Abrous
Mol Psychiatry. 2021-09-15
10.1038/s41380-021-01276-x

Neural Substrates of Incidental Associations and Mediated Learning: The Role of Cannabinoid Receptors.
Christina Ioannidou, Arnau Busquets-Garcia, Guillaume Ferreira, Giovanni Marsicano
Front. Behav. Neurosci.. 2021-08-06
10.3389/fnbeh.2021.722796

Communication and social interaction in the cannabinoid‐type 1 receptor null mouse: Implications for autism spectrum disorder
William Fyke, Marika Premoli, Victor Echeverry Alzate, José A. López‐Moreno, Valerie Lemaire‐Mayo, Wim E. Crusio, Giovanni Marsicano, Markus Wöhr, Susanna Pietropaolo
Autism Research. 2021-06-26
10.1002/aur.2562

CB1R-dependent regulation of astrocyte physiology and astrocyte-neuron interactions
Ana Covelo, Abel Eraso-Pichot, Ignacio Fernández-Moncada, Román Serrat, Giovanni Marsicano
Neuropharmacology. 2021-06-01
10.1016/j.neuropharm.2021.108678

Hypothalamic bile acid-TGR5 signaling protects from obesity.
Ashley Castellanos-Jankiewicz, Omar Guzmán-Quevedo, Valérie S. Fénelon, Philippe Zizzari, Carmelo Quarta, Luigi Bellocchio, Anne Tailleux, Julie Charton, Daniela Fernandois, Marcus Henricsson, Catherine Piveteau, Vincent Simon, Camille Allard, Sandrine Quemener, Valentine Guinot, Nathalie Hennuyer, Alessia Perino, Alexia Duveau, Marlène Maitre, Thierry Leste-Lasserre, Samantha Clark, Nathalie Dupuy, Astrid Cannich, Delphine Gonzales, Benoit Deprez, Gilles Mithieux, David Dombrowicz, Fredrik Bäckhed, Vincent Prevot, Giovanni Marsicano, Bart Staels, Kristina Schoonjans, Daniela Cota
Cell Metabolism. 2021-04-01
10.1016/j.cmet.2021.04.009

Long-lasting synaptic regulation of dopamine neurons by astrocytes in the Ventral Tegmental Area
Linda Requie, Marta Gómez-Gonzalo, Francesca Managò, Mauro Congiu, Marcello Melone, Angela Chiavegato, Arianna Arianna, Giada Pacinelli, Marsicano Giovanni, Francesco Papaleo, Anna Muntoni, Fiorenzo Conti, Giorgio Carmignoto
. 2021-03-23
10.21203/rs.3.rs-301561/v1

Spinal astroglial cannabinoid receptors control pathological tremor
Eva Maria Meier Carlsen, Sarah Falk, Urszula Skupio, Laurie Robin, Antonio C. Pagano Zottola, Giovanni Marsicano, Jean-François Perrier
Nat Neurosci. 2021-03-18
10.1038/s41593-021-00818-4

Cannabis and exercise: Effects of Δ9-tetrahydrocannabinol on preference and motivation for wheel-running in mice
Imane Hurel, Carolina Muguruza, Bastien Redon, Giovanni Marsicano, Francis Chaouloff
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2021-03-01
10.1016/j.pnpbp.2020.110117

Astroglial calcium transfer from endoplasmic reticulum to mitochondria determines synaptic integration
Roman Serrat, Ana Covelo, Vladimir Kouskoff, Sebastien Delcasso, Andrea Ruiz, Nicolas Chenouard, Carol Stella, Corinne Blancard, Benedicte Salin, Francisca Julio-Kalajzić, Astrid Cannich, Federico Massa, Marjorie Varilh, Severine Deforges, Laurie M. Robin, Diego De Stefani, Arnau Busquets-Garcia, Frederic Gambino, Anna Beyeler, Sandrine Pouvreau, Giovanni Marsicano
Preprint bioRxiv. 2020-12-08
10.1101/2020.12.08.415620

A Novel Cortical Mechanism for Top-Down Control of Water Intake.
Zhe Zhao, Edgar Soria-Gómez, Marjorie Varilh, Ana Covelo, Francisca Julio-Kalajzić, Astrid Cannich, Adriana Castiglione, Léonie Vanhoutte, Alexia Duveau, Philippe Zizzari, Anna Beyeler, Daniela Cota, Luigi Bellocchio, Arnau Busquets-Garcia, Giovanni Marsicano
Current Biology. 2020-12-01
10.1016/j.cub.2020.09.011

Cannabinoid-induced motor dysfunction via autophagy inhibition
Cristina Blázquez, Andrea Ruiz-Calvo, Raquel Bajo-Grañeras, Jerome M. Baufreton, Eva Resel, Marjorie Varilh, Antonio C. Pagano Zottola, Yamuna Mariani, Astrid Cannich, José A. Rodríguez-Navarro, Giovanni Marsicano, Ismael Galve-Roperh, Luigi Bellocchio, Manuel Guzmán
Autophagy. 2020-10-20
10.1080/15548627.2020.1827560

Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons
Maria‐Carmen Medrano, Imane Hurel, Emma Mesguich, Bastien Redon, Christopher Stevens, François Georges, Miriam Melis, Giovanni Marsicano, Francis Chaouloff
Addiction Biology. 2020-10-05
10.1111/adb.12967

Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination
Cristina Blázquez, Andrea Ruiz-Calvo, Raquel Bajo-Grañeras, Jérôme M Baufreton, Eva Resel, Marjorie Varilh, Antonio C Pagano Zottola, Yamuna Mariani, Astrid Cannich, José A Rodríguez-Navarro, Giovanni Marsicano, Ismael Galve-Roperh, Luigi Bellocchio, Manuel Guzmán
eLife. 2020-08-10
10.7554/eLife.56811

Sex‐dependent pharmacological profiles of the synthetic cannabinoid MMB‐Fubinaca
José F. Oliveira da Cruz, Christina Ioannidou, Antonio C. Pagano Zottola, Carolina Muguruza, Paula Gomez‐Sotres, Monica Fernandez, Luis F. Callado, Giovanni Marsicano, Arnau Busquets‐Garcia
Addiction Biology. 2020-08-03
10.1111/adb.12940

Specific Hippocampal Interneurons Shape Consolidation of Recognition Memory
Jose F. Oliveira da Cruz, Arnau Busquets-Garcia, Zhe Zhao, Marjorie Varilh, Gianluca Lavanco, Luigi Bellocchio, Laurie Robin, Astrid Cannich, Francisca Julio-Kalajzić, Thierry Lesté-Lasserre, Marlène Maître, Filippo Drago, Giovanni Marsicano, Edgar Soria-Gómez
Cell Reports. 2020-08-01
10.1016/j.celrep.2020.108046

Glucose metabolism links astroglial mitochondria to cannabinoid effects
Daniel Jimenez-Blasco, Arnau Busquets-Garcia, Etienne Hebert-Chatelain, Roman Serrat, Carlos Vicente-Gutierrez, Christina Ioannidou, Paula Gómez-Sotres, Irene Lopez-Fabuel, Monica Resch-Beusher, Eva Resel, Dorian Arnouil, Dave Saraswat, Marjorie Varilh, Astrid Cannich, Francisca Julio-Kalajzic, Itziar Bonilla-Del Río, Angeles Almeida, Nagore Puente, Svein Achicallende, Maria-Luz Lopez-Rodriguez, Charlotte Jollé, Nicole Déglon, Luc Pellerin, Charlène Josephine, Gilles Bonvento, Aude Panatier, Beat Lutz, Pier-Vincenzo Piazza, Manuel Guzmán, Luigi Bellocchio, Anne-Karine Bouzier-Sore, Pedro Grandes, Juan P. Bolaños, Giovanni Marsicano
Nature. 2020-07-08
10.1038/s41586-020-2470-y

Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
Emma Puighermanal, Laia Castell, Anna Esteve-Codina, Su Melser, Konstantin Kaganovsky, Charleine Zussy, Jihane Boubaker-Vitre, Marta Gut, Stephanie Rialle, Christoph Kellendonk, Elisenda Sanz, Albert Quintana, Giovanni Marsicano, Miquel Martin, Marcelo Rubinstein, Jean-Antoine Girault, Jun B. Ding, Emmanuel Valjent
Nat Commun. 2020-04-23
10.1038/s41467-020-15716-9

Structural basis of astrocytic Ca2+ signals at tripartite synapses
Misa Arizono, V. V. G. Krishna Inavalli, Aude Panatier, Thomas Pfeiffer, Julie Angibaud, Florian Levet, Mirelle J. T. Ter Veer, Jillian Stobart, Luigi Bellocchio, Katsuhiko Mikoshiba, Giovanni Marsicano, Bruno Weber, Stéphane H. R. Oliet, U. Valentin Nägerl
Nat Commun. 2020-04-20
10.1038/s41467-020-15648-4

Cannabinoid control of olfactory processes: The where matters
Geoffrey Terral, Giovanni Marsicano, Pedro Grandes, Edgar Soria-Gómez
Genes. 2020-04-16
10.3390/genes11040431

A new mutant mouse model lacking mitochondrial-associated CB1 receptor
Antonio C. Pagano Zottola, Edgar Soria-Gomez, Itziar Bonilla-del-Río, Carolina Muguruza, Geoffrey Terral, Laurie M. Robin, José F. Oliveira da Cruz, Bastien Redon, Thierry Lesté-Lasserre, Tarson Tolentino-Cortes, Nagore Puente, Gabriel Barreda-Gómez, Francis Chaouloff, Luis F. Callado, Pedro Grandes, Giovanni Marsicano, Luigi Bellocchio
Preprint bioRxiv. 2020-03-31
10.1101/2020.03.30.009472

POMC neurons functional heterogeneity relies on mTORC1 signaling.
Nicolas Saucisse, Wilfrid Mazier, Vincent Simon, Elke Binder, Caterina Catania, Luigi Bellocchio, Roman A. Romanov, Isabelle Matias, Philippe Zizzari, Stephane Leon, Carmelo Quarta, Astrid Cannich, Kana Meece, Delphine Gonzales, Samantha Clark, Julia M. Becker, Giles S.H. Yeo, Florian T. Merkle, Sharon L. Wardlaw, Tibor Harkany, Federico Massa, Giovanni Marsicano, Daniela Cota
. 2020-03-26
10.1101/2020.03.25.007765

Synaptic Functions of Type-1 Cannabinoid Receptors in Inhibitory Circuits of the Anterior Piriform Cortex
Geoffrey Terral, Marjorie Varilh, Astrid Cannich, Federico Massa, Guillaume Ferreira, Giovanni Marsicano
Neuroscience. 2020-03-01
10.1016/j.neuroscience.2020.03.002

Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity
Michelle Corkrum, Ana Covelo, Justin Lines, Luigi Bellocchio, Marc Pisansky, Kelvin Loke, Ruth Quintana, Patrick E. Rothwell, Rafael Lujan, Giovanni Marsicano, Eduardo D. Martin, Mark J. Thomas, Paulo Kofuji, Alfonso Araque
Neuron. 2020-03-01
10.1016/j.neuron.2019.12.026

Alpha technology: A powerful tool to detect mouse brain intracellular signaling events
Marion Zanese, Giovanni Tomaselli, Valérie Roullot-Lacarrière, Maïté Moreau, Luigi Bellocchio, Agnès Grel, Giovanni Marsicano, Nathalie Sans, Monique Vallée, Jean-Michel Revest
Journal of Neuroscience Methods. 2020-02-01
10.1016/j.jneumeth.2019.108543

An Alternative Maze to Assess Novel Object Recognition in Mice
José Fernando Oliveira da Cruz, Maria Gomis-Gonzalez, Rafael Maldonado, Giovanni Marsicano, Andrés Ozaita, Arnau Busquets-Garcia
BIO-PROTOCOL. 2020-01-01
10.21769/bioprotoc.3651

The ergogenic impact of the glucocorticoid prednisolone does not translate into increased running motivation in mice
Bastien Redon, Claire Violleau, François Georges, Giovanni Marsicano, Francis Chaouloff
Psychoneuroendocrinology. 2020-01-01
10.1016/j.psyneuen.2019.104489

mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability
Wilfrid Mazier, Nicolas Saucisse, Vincent Simon, Astrid Cannich, Giovanni Marsicano, Federico Massa, Daniela Cota
Molecular Metabolism. 2019-10-01
10.1016/j.molmet.2019.08.005

Top-down control of water intake by the endocannabinoid system
Zhe Zhao, Edgar Soria-Gómez, Marjorie Varilh, Francisca Julio-Kalajzić, Astrid Cannich, Adriana Castiglione, Léonie Vanhoutte, Alexia Duveau, Philippe Zizzari, Anna Beyeler, Daniela Cota, Luigi Bellocchio, Arnau Busquets-Garcia, Giovanni Marsicano
Preprint bioRxiv. 2019-08-09
10.1101/729970

CB1 Receptors in the Anterior Piriform Cortex Control Odor Preference Memory
Geoffrey Terral, Arnau Busquets-Garcia, Marjorie Varilh, Svein Achicallende, Astrid Cannich, Luigi Bellocchio, Itziar Bonilla-Del Río, Federico Massa, Nagore Puente, Edgar Soria-Gomez, Pedro Grandes, Guillaume Ferreira, Giovanni Marsicano
Current Biology. 2019-08-01
10.1016/j.cub.2019.06.041

Beyond the activity-based anorexia model: Reinforcing values of exercise and feeding examined in stressed adolescent Male and female mice
Imane Hurel, Bastien Redon, Amandine Scocard, Meryl Malezieux, Giovanni Marsicano, Francis Chaouloff
Front. Pharmacol.. 2019-05-17
10.3389/fphar.2019.00587

The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors.
Carolina Muguruza, Bastien Redon, Giulia R. Fois, Imane Hurel, Amandine Scocard, Claire Nguyen, Christopher Stevens, Edgar Soria-Gomez, Marjorie Varilh, Astrid Cannich, Justine Daniault, Arnau Busquets-Garcia, Teresa Pelliccia, Stéphanie Caillé, François Georges, Giovanni Marsicano, Francis Chaouloff
JCI Insight. 2019-03-07
10.1172/jci.insight.126190

An Operant Conditioning Task to Assess the Choice between Wheel Running and Palatable Food in Mice.
Bastien Redon, Imane Hurel, Giovanni Marsicano, Francis Chaouloff
BIO-PROTOCOL. 2019-01-01
10.21769/bioprotoc.3381

Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus.
Ana Gutiérrez-Rodríguez, Itziar Bonilla-Del Río, Nagore Puente, Sonia M. Gómez-Urquijo, Christine J. Fontaine, Jon Egaña-Huguet, Izaskun Elezgarai, Sabine Ruehle, Beat Lutz, Laurie M. Robin, Edgar Soria-Gómez, Luigi Bellocchio, Jalindar D. Padwal, Mario van der Stelt, Juan Mendizabal-Zubiaga, Leire Reguero, Almudena Ramos, Inmaculada Gerrikagoitia, Giovanni Marsicano, Pedro Grandes
Glia. 2018-02-26
10.1002/glia.23314

Ribosomal Protein S6 Phosphorylation Is Involved in Novelty-Induced Locomotion, Synaptic Plasticity and mRNA Translation.
Emma Puighermanal, Anne Biever, Vincent Pascoli, Su Melser, Marine Pratlong, Laura Cutando, Stephanie Rialle, Dany Severac, Jihane Boubaker-Vitre, Oded Meyuhas, Giovanni Marsicano, Christian Lüscher, Emmanuel Valjent
Front. Mol. Neurosci.. 2017-12-21
10.3389/fnmol.2017.00419

Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors.
Andrea Ruiz-Calvo, Irene B Maroto, Raquel Bajo-Grañeras, Anna Chiarlone, Ángel Gaudioso, José J Ferrero, Eva Resel, José Sánchez-Prieto, José A Rodríguez-Navarro, Giovanni Marsicano, Ismael Galve-Roperh, Luigi Bellocchio, Manuel Guzmán
Cerebral Cortex. 2017-10-31
10.1093/cercor/bhx285

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.
Inigo Ruiz de Azua, Giacomo Mancini, Raj Kamal Srivastava, Alejandro Aparisi Rey, Pierre Cardinal, Laura Tedesco, Cristina Maria Zingaretti, Antonia Sassmann, Carmelo Quarta, Claudia Schwitter, Andrea Conrad, Nina Wettschureck, V. Kiran Vemuri, Alexandros Makriyannis, Jens Hartwig, Maria Mendez-Lago, Laura Bindila, Krisztina Monory, Antonio Giordano, Saverio Cinti, Giovanni Marsicano, Stefan Offermanns, Enzo Nisoli, Uberto Pagotto, Daniela Cota, Beat Lutz
Journal of Clinical Investigation. 2017-10-16
10.1172/jci83626

Synapse-specific astrocyte gating of amygdala-related behavior.
Mario Martin-Fernandez, Stephanie Jamison, Laurie M Robin, Zhe Zhao, Eduardo D Martin, Juan Aguilar, Michael A Benneyworth, Giovanni Marsicano, Alfonso Araque
Nat Neurosci. 2017-09-25
10.1038/nn.4649

CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity.
Arnau Busquets-Garcia, Jaideep Bains, Giovanni Marsicano
Neuropsychopharmacology. 2017-09-01
10.1038/npp.2017.206

[Mitochondria link between cannabinoid and memory].
Étienne Hébert-Chatelain, Giovanni Marsicano
Med Sci (Paris). 2017-06-01
10.1051/medsci/20173306007

CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal.
Rocio Saravia, África Flores, Ainhoa Plaza-Zabala, Arnau Busquets-Garcia, Antoni Pastor, Rafael de la Torre, Vincenzo Di Marzo, Giovanni Marsicano, Andrés Ozaita, Rafael Maldonado, Fernando Berrendero
Biological Psychiatry. 2017-04-01
10.1016/j.biopsych.2016.07.007

The CB1 Receptor as the Cornerstone of Exostasis.
Pier Vincenzo Piazza, Daniela Cota, Giovanni Marsicano
Neuron. 2017-03-01
10.1016/j.neuron.2017.02.002

Pregnenolone blocks cannabinoid-induced acute psychotic-like states in mice.
A Busquets-Garcia, E Soria-Gómez, B Redon, Y Mackenbach, M Vallée, F Chaouloff, M Varilh, G Ferreira, P-V Piazza, G Marsicano
Mol Psychiatry. 2017-02-21
10.1038/mp.2017.4

Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases.
Marc P. Baggelaar, Annelot C. M. van Esbroeck, Eva J. van Rooden, Bogdan I. Florea, Herman S. Overkleeft, Giovanni Marsicano, Francis Chaouloff, Mario van der Stelt
ACS Chem. Biol.. 2017-02-13
10.1021/acschembio.6b01052

Representation-mediated Aversion as a Model to Study Psychotic-like States in Mice.
Arnau Busquets-Garcia, Edgar Soria-Gómez, Guillaume Ferreira, Giovanni Marsicano
BIO-PROTOCOL. 2017-01-01
10.21769/bioprotoc.2358

Functional Analysis of Mitochondrial CB1 Cannabinoid Receptors (mtCB1) in the Brain.
Su Melser, Antonio C. Pagano Zottola, Roman Serrat, Nagore Puente, Pedro Grandes, Giovanni Marsicano, Etienne Hebert-Chatelain
Methods in Enzymology. 2017-01-01
10.1016/bs.mie.2017.06.023

Cannabinoids and mitochondria
Etienne Hebert-Chatelain, Giovanni Marsicano, Tifany Desprez
Endocannabinoids and Lipid Mediators in Brain Functions. 2017-01-01
10.1007/978-3-319-57371-7_8

Role of endocannabinoids in synaptic plasticity and memory
Simon A. Bura, Rafael C. Almada, Beat Lutz, Giovanni Marsicano, Carsten T. Wotjak
Reference Module in Neuroscience and Biobehavioral Psychology. 2017-01-01
10.1016/B978-0-12-809324-5.02289-6

Interacting Cannabinoid and Opioid Receptors in the Nucleus Accumbens Core Control Adolescent Social Play.
Antonia Manduca, Olivier Lassalle, Marja Sepers, Patrizia Campolongo, Vincenzo Cuomo, Giovanni Marsicano, Brigitte Kieffer, Louk J. M. J Vanderschuren, Viviana Trezza, Olivier J. J. Manzoni
Front. Behav. Neurosci.. 2016-11-16
10.3389/fnbeh.2016.00211

A cannabinoid link between mitochondria and memory.
Etienne Hebert-Chatelain, Tifany Desprez, Román Serrat, Luigi Bellocchio, Edgar Soria-Gomez, Arnau Busquets-Garcia, Antonio Christian Pagano Zottola, Anna Delamarre, Astrid Cannich, Peggy Vincent, Marjorie Varilh, Laurie M. Robin, Geoffrey Terral, M. Dolores García-Fernández, Michelangelo Colavita, Wilfrid Mazier, Filippo Drago, Nagore Puente, Leire Reguero, Izaskun Elezgarai, Jean-William Dupuy, Daniela Cota, Maria-Luz Lopez-Rodriguez, Gabriel Barreda-Gómez, Federico Massa, Pedro Grandes, Giovanni Bénard, Giovanni Marsicano
Nature. 2016-11-01
10.1038/nature20127

Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration.
Juan Mendizabal-Zubiaga, Su Melser, Giovanni Bénard, Almudena Ramos, Leire Reguero, Sergio Arrabal, Izaskun Elezgarai, Inmaculada Gerrikagoitia, Juan Suarez, Fernando Rodríguez De Fonseca, Nagore Puente, Giovanni Marsicano, Pedro Grandes
Front. Physiol.. 2016-10-25
10.3389/fphys.2016.00476

Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation.
Arnau Busquets-Garcia, Maria Gomis-González, Raj Kamal Srivastava, Laura Cutando, Antonio Ortega-Alvaro, Sabine Ruehle, Floortje Remmers, Laura Bindila, Luigi Bellocchio, Giovanni Marsicano, Beat Lutz, Rafael Maldonado, Andrés Ozaita
Proc Natl Acad Sci USA. 2016-08-15
10.1073/pnas.1525066113

Anatomical characterization of the cannabinoid CB1 receptor in cell-type-specific mutant mouse rescue models.
Ana Gutiérrez-Rodríguez, Nagore Puente, Izaskun Elezgarai, Sabine Ruehle, Beat Lutz, Leire Reguero, Inmaculada Gerrikagoitia, Giovanni Marsicano, Pedro Grandes
J. Comp. Neurol.. 2016-07-08
10.1002/cne.24066

Layer-specific potentiation of network GABAergic inhibition in the CA1 area of the hippocampus.
Michelangelo Colavita, Geoffrey Terral, Clement E. Lemercier, Filippo Drago, Giovanni Marsicano, Federico Massa
Sci Rep. 2016-06-27
10.1038/srep28454

MitoBrain, Putting energy into the brain.
Giovanni Benard, Erwan Bezard, Giovanni Marsicano, Sandrine Pouvreau
Neurobiology of Disease. 2016-06-01
10.1016/j.nbd.2016.03.021

Cannabinoid receptor type-1: breaking the dogmas.
Arnau Busquets Garcia, Edgar Soria-Gomez, Luigi Bellocchio, Giovanni Marsicano
F1000Res. 2016-05-24
10.12688/f1000research.8245.1

Astroglial type-1 cannabinoid receptor (CB1): A new player in the tripartite synapse.
J.F. Oliveira da Cruz, L.M. Robin, F. Drago, G. Marsicano, M. Metna-Laurent
Neuroscience. 2016-05-01
10.1016/j.neuroscience.2015.05.002

Running per se stimulates the dendritic arbor of newborn dentate granule cells in mouse hippocampus in a duration-dependent manner.
Sandrine Dostes, Sarah Dubreucq, Elodie Ladevèze, Giovanni Marsicano, Djoher N. Abrous, Francis Chaouloff, Muriel Koehl
Hippocampus. 2015-12-08
10.1002/hipo.22551

Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid.
M.A. De Luca, Z. Bimpisidis, M. Melis, M. Marti, P. Caboni, V. Valentini, G. Margiani, N. Pintori, I. Polis, G. Marsicano, L.H. Parsons, G. Di Chiara
Neuropharmacology. 2015-12-01
10.1016/j.neuropharm.2015.08.041

The endocannabinoid system in guarding against fear, anxiety and stress.
Beat Lutz, Giovanni Marsicano, Rafael Maldonado, Cecilia J. Hillard
Nat Rev Neurosci. 2015-12-01
10.1038/nrn4036

Differential Control of Cocaine Self-Administration by GABAergic and Glutamatergic CB1 Cannabinoid Receptors.
Elena Martín-García, Lucie Bourgoin, Adeline Cathala, Fernando Kasanetz, Miguel Mondesir, Ana Gutiérrez-Rodriguez, Leire Reguero, Jean- François Fiancette, Pedro Grandes, Umberto Spampinato, Rafael Maldonado, Pier Vincenzo Piazza, Giovanni Marsicano, Véronique Deroche-Gamonet
Neuropsychopharmacol. 2015-11-27
10.1038/npp.2015.351

The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.
Francisco J. Bermudez-Silva, Silvana Y. Romero-Zerbo, Magalie Haissaguerre, Inmaculada Ruz-Maldonado, Said Lhamyani, Rajaa El Bekay, Antoine Tabarin, Giovanni Marsicano, Daniela Cota
Dis. Model. Mech.. 2015-11-12
10.1242/dmm.020750

Habenular CB1 Receptors Control the Expression of Aversive Memories.
Edgar Soria-Gómez, Arnau Busquets-Garcia, Fei Hu, Amine Mehidi, Astrid Cannich, Liza Roux, Ines Louit, Lucille Alonso, Theresa Wiesner, Francois Georges, Danièle Verrier, Peggy Vincent, Guillaume Ferreira, Minmin Luo, Giovanni Marsicano
Neuron. 2015-10-01
10.1016/j.neuron.2015.08.035

Dissecting the cannabinergic control of behavior: The where matters.
Arnau Busquets-Garcia, Tifany Desprez, Mathilde Metna-Laurent, Luigi Bellocchio, Giovanni Marsicano, Edgar Soria-Gomez
BioEssays. 2015-08-11
10.1002/bies.201500046

Duration- and environment-dependent effects of repeated voluntary exercise on anxiety and cued fear in mice.
Sarah Dubreucq, Giovanni Marsicano, Francis Chaouloff
Behavioural Brain Research. 2015-04-01
10.1016/j.bbr.2014.12.042

Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 receptors located on glutamatergic neurons and on astrocytes.
Ilaria Belluomo, Isabelle Matias, Camille Pernègre, Giovanni Marsicano, Francis Chaouloff
J. Neurochem.. 2015-02-25
10.1111/jnc.13044

Cannabinoid type 1 (CB1) receptors on Sim1-expressing neurons regulate energy expenditure in male mice.
Pierre Cardinal, Luigi Bellocchio, Omar Guzmán-Quevedo, Caroline André, Samantha Clark, Melissa Elie, Thierry Leste-Lasserre, Delphine Gonzales, Astrid Cannich, Giovanni Marsicano, Daniela Cota
Endocrinology. 2015-02-01
10.1210/en.2014-1437

Cannabinoid control of fear responses
Mathilde Metna-Laurent, Giovanni Marsicano, Edgar Soria-Gómez
Cannabinoid Modulation of Emotion, Memory, and Motivation. 2015-01-01
10.1007/978-1-4939-2294-9_6

Rising stars: modulation of brain functions by astroglial type-1 cannabinoid receptors.
Mathilde Metna-Laurent, Giovanni Marsicano
Glia. 2014-12-01
10.1002/glia.22773

New insights on food intake control by olfactory processes: the emerging role of the endocannabinoid system.
Edgar Soria-Gomez, Luigi Bellocchio, Giovanni Marsicano
Molecular and Cellular Endocrinology. 2014-11-01
10.1016/j.mce.2014.09.023

CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin.
Pierre Cardinal, Caroline André, Carmelo Quarta, Luigi Bellocchio, Samantha Clark, Melissa Elie, Thierry Leste-Lasserre, Marlene Maitre, Delphine Gonzales, Astrid Cannich, Uberto Pagotto, Giovanni Marsicano, Daniela Cota
Molecular Metabolism. 2014-10-01
10.1016/j.molmet.2014.07.004

Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats.
M. Melis, C. Sagheddu, M. De Felice, A. Casti, C. Madeddu, S. Spiga, A. L. Muntoni, K. Mackie, G. Marsicano, G. Colombo, M. P. Castelli, M. Pistis
Journal of Neuroscience. 2014-09-17
10.1523/jneurosci.1844-14.2014

Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor.
Etienne Hebert-Chatelain, Leire Reguero, Nagore Puente, Beat Lutz, Francis Chaouloff, Rodrigue Rossignol, Pier-Vincenzo Piazza, Giovanni Benard, Pedro Grandes, Giovanni Marsicano
Molecular Metabolism. 2014-07-01
10.1016/j.molmet.2014.03.007

Studying mitochondrial CB1 receptors: Yes we can.
Etienne Hebert-Chatelain, Leire Reguero, Nagore Puente, Beat Lutz, Francis Chaouloff, Rodrigue Rossignol, Pier-Vincenzo Piazza, Giovanni Benard, Pedro Grandes, Giovanni Marsicano
Molecular Metabolism. 2014-07-01
10.1016/j.molmet.2014.03.008

Cannabinoid type-1 receptors in the paraventricular nucleus of the hypothalamus inhibit stimulated food intake.
E. Soria-Gómez, F. Massa, L. Bellocchio, P.E. Rueda-Orozco, P. Ciofi, D. Cota, S.H.R. Oliet, O. Prospéro-García, G. Marsicano
Neuroscience. 2014-03-01
10.1016/j.neuroscience.2014.01.005

Pregnenolone can protect the brain from cannabis intoxication (Science (94))

Science. 2014-02-27
10.1126/science.343.6174.969-b

The endocannabinoid system controls food intake via olfactory processes.
Edgar Soria-Gómez, Luigi Bellocchio, Leire Reguero, Gabriel Lepousez, Claire Martin, Mounir Bendahmane, Sabine Ruehle, Floor Remmers, Tifany Desprez, Isabelle Matias, Theresa Wiesner, Astrid Cannich, Antoine Nissant, Aya Wadleigh, Hans-Christian Pape, Anna Paola Chiarlone, Carmelo Quarta, Daniéle Verrier, Peggy Vincent, Federico Massa, Beat Lutz, Manuel Guzmán, Hirac Gurden, Guillaume Ferreira, Pierre-Marie Lledo, Pedro Grandes, Giovanni Marsicano
Nat Neurosci. 2014-02-09
10.1038/nn.3647

Pregnenolone can protect the brain from cannabis intoxication.
Monique Vallée, Sergio Vitiello, Luigi Bellocchio, Etienne Hébert-Chatelain, Stéphanie Monlezun, Elena Martin-Garcia, Fernando Kasanetz, Gemma L. Baillie, Francesca Panin, Adeline Cathala, Valérie Roullot-Lacarrière, Sandy Fabre, Dow P. Hurst, Diane L. Lynch, Derek M. Shore, Véronique Deroche-Gamonet, Umberto Spampinato, Jean-Michel Revest, Rafael Maldonado, Patricia H. Reggio, Ruth A. Ross, Giovanni Marsicano, Pier Vincenzo Piazza
Science. 2014-01-02
10.1126/science.1243985

Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists.
Gareth Pryce, Cristina Visintin, Sreeram V. Ramagopalan, Sarah Al-Izki, Lia E. De Faveri, Rosamond A. Nuamah, Charles A. Mein, Alexandre Montpetit, Alison J. Hardcastle, Gijs Kooij, Helga E. de Vries, Sandra Amor, Sarah A. Thomas, Catherine Ledent, Giovanni Marsicano, Beat Lutz, Alan J. Thompson, David L. Selwood, Gavin Giovannoni, David Baker
The FASEB Journal. 2014-01-01
10.1096/fj.13-239442

Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis.
C. Glangetas, D. Girard, L. Groc, G. Marsicano, F. Chaouloff, F. Georges
Journal of Neuroscience. 2013-12-11
10.1523/jneurosci.3175-13.2013

Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis
C. Glangetas, D. Girard, L. Groc, G. Marsicano, F. Chaouloff, F. Georges
Journal of Neuroscience. 2013-12-11
10.1523/JNEUROSCI.3175-13.2013

Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes.
Barbara Bosier, Luigi Bellocchio, Mathilde Metna-Laurent, Edgar Soria-Gomez, Isabelle Matias, Etienne Hebert-Chatelain, Astrid Cannich, Marlène Maitre, Thierry Leste-Lasserre, Pierre Cardinal, Juan Mendizabal-Zubiaga, Miren Josune Canduela, Leire Reguero, Emmanuel Hermans, Pedro Grandes, Daniela Cota, Giovanni Marsicano
Molecular Metabolism. 2013-11-01
10.1016/j.molmet.2013.08.001

Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats.
Heng Zhou, Zhi Zhang, Haidong Wei, Feng Wang, Fan Guo, Zijun Gao, Giovanni Marsicano, Qiang Wang, Lize Xiong
Brain Research. 2013-09-01
10.1016/j.brainres.2013.07.006

Glycogen synthase kinase-3β is involved in electroacupuncture pretreatment via the cannabinoid CB1 receptor in ischemic stroke.
Haidong Wei, Xi Yao, Lifang Yang, Shiquan Wang, Fan Guo, Heng Zhou, Giovanni Marsicano, Qiang Wang, Lize Xiong
Mol Neurobiol. 2013-08-14
10.1007/s12035-013-8524-5

Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions.
S. Ruehle, F. Remmers, H. Romo-Parra, F. Massa, M. Wickert, S. Wortge, M. Haring, N. Kaiser, G. Marsicano, H.-C. Pape, B. Lutz
Journal of Neuroscience. 2013-06-19
10.1523/jneurosci.4171-12.2013

Ventral tegmental area cannabinoid type-1 receptors control voluntary exercise performance.
Sarah Dubreucq, Audrey Durand, Isabelle Matias, Giovanni Bénard, Elodie Richard, Edgar Soria-Gomez, Christelle Glangetas, Laurent Groc, Aya Wadleigh, Federico Massa, Dusan Bartsch, Giovanni Marsicano, Francois Georges, Francis Chaouloff
Biological Psychiatry. 2013-05-01
10.1016/j.biopsych.2012.10.025

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade.
L. Bellocchio, E. Soria-Gomez, C. Quarta, M. Metna-Laurent, P. Cardinal, E. Binder, A. Cannich, A. Delamarre, M. Haring, M. Martin-Fontecha, D. Vega, T. Leste-Lasserre, D. Bartsch, K. Monory, B. Lutz, F. Chaouloff, U. Pagotto, M. Guzman, D. Cota, G. Marsicano
Proceedings of the National Academy of Sciences. 2013-03-04
10.1073/pnas.1218573110

Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus.
Frauke Steindel, Raissa Lerner, Martin Häring, Sabine Ruehle, Giovanni Marsicano, Beat Lutz, Krisztina Monory
J. Neurochem.. 2013-02-13
10.1111/jnc.12137

Two-photon excitation STED microscopy in two colors in acute brain slices.
Philipp Bethge, Ronan Chéreau, Elena Avignone, Giovanni Marsicano, U. Valentin Nägerl
Biophysical Journal. 2013-02-01
10.1016/j.bpj.2012.12.054

Dissociation of the pharmacological effects of THC by mTOR blockade.
Emma Puighermanal, Arnau Busquets-Garcia, Maria Gomis-González, Giovanni Marsicano, Rafael Maldonado, Andrés Ozaita
Neuropsychopharmacol. 2013-01-28
10.1038/npp.2013.31

Striatal GABAergic and cortical glutamatergic neurons mediate contrasting effects of cannabinoids on cortical network synchrony.
C. Sales-Carbonell, P. E. Rueda-Orozco, E. Soria-Gomez, G. Buzsaki, G. Marsicano, D. Robbe
Proceedings of the National Academy of Sciences. 2012-12-26
10.1073/pnas.1217144110

Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.
F. A. Pamplona, J. Ferreira, O. Menezes de Lima, F. S. Duarte, A. F. Bento, S. Forner, J. G. Villarinho, L. Bellocchio, C. T. Wotjak, R. Lerner, K. Monory, B. Lutz, C. Canetti, I. Matias, J. B. Calixto, G. Marsicano, M. Z. P. Guimaraes, R. N. Takahashi
Proceedings of the National Academy of Sciences. 2012-11-12
10.1073/pnas.1202906109

Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice.
Pierre Cardinal, Luigi Bellocchio, Samantha Clark, Astrid Cannich, Matthias Klugmann, Beat Lutz, Giovanni Marsicano, Daniela Cota
Endocrinology. 2012-09-01
10.1210/en.2012-1405

Un nouveau biomarqueur de l’obésité humaine : les endocannabinoïdes salivaires
B. Gatta-Cherifi, I. Matias, A. Tabarin, S. Clark, T. Lestte-Lasserre, G. Marsicano, P.V. Piazza, D. Cota
Annales d'Endocrinologie. 2012-09-01
10.1016/j.ando.2012.07.733

Endocannabinoids measurement in human saliva as potential biomarker of obesity.
Isabelle Matias, Blandine Gatta-Cherifi, Antoine Tabarin, Samantha Clark, Thierry Leste-Lasserre, Giovanni Marsicano, Pier Vincenzo Piazza, Daniela Cota
PLoS ONE. 2012-07-31
10.1371/journal.pone.0042399

Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo.
Wolfgang Jacob, Rudolph Marsch, Giovanni Marsicano, Beat Lutz, Carsten T. Wotjak
Neurobiology of Learning and Memory. 2012-07-01
10.1016/j.nlm.2012.04.008

Bimodal control of fear-coping strategies by CB₁ cannabinoid receptors.
M. Metna-Laurent, E. Soria-Gomez, D. Verrier, M. Conforzi, P. Jego, P. Lafenetre, G. Marsicano
Journal of Neuroscience. 2012-05-23
10.1523/jneurosci.1054-12.2012

Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice.
Sarah Dubreucq, Isabelle Matias, Pierre Cardinal, Martin Häring, Beat Lutz, Giovanni Marsicano, Francis Chaouloff
Neuropsychopharmacol. 2012-03-21
10.1038/npp.2012.36

Mitochondrial CB₁ receptors regulate neuronal energy metabolism.
Giovanni Bénard, Federico Massa, Nagore Puente, Joana Lourenço, Luigi Bellocchio, Edgar Soria-Gómez, Isabel Matias, Anna Delamarre, Mathilde Metna-Laurent, Astrid Cannich, Etienne Hebert-Chatelain, Christophe Mulle, Silvia Ortega-Gutiérrez, Mar Martín-Fontecha, Matthias Klugmann, Stephan Guggenhuber, Beat Lutz, Jürg Gertsch, Francis Chaouloff, María Luz López-Rodríguez, Pedro Grandes, Rodrigue Rossignol, Giovanni Marsicano
Nat Neurosci. 2012-03-04
10.1038/nn.3053

Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD.
Jing Han, Philip Kesner, Mathilde Metna-Laurent, Tingting Duan, Lin Xu, Francois Georges, Muriel Koehl, Djoher Nora Abrous, Juan Mendizabal-Zubiaga, Pedro Grandes, Qingsong Liu, Guang Bai, Wei Wang, Lize Xiong, Wei Ren, Giovanni Marsicano, Xia Zhang
Cell. 2012-03-01
10.1016/j.cell.2012.01.037

Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors.
S. Dubreucq, S. Kambire, M. Conforzi, M. Metna-Laurent, A. Cannich, E. Soria-Gomez, E. Richard, G. Marsicano, F. Chaouloff
Neuroscience. 2012-03-01
10.1016/j.neuroscience.2011.08.049

Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses
Maddalena D. Caiati, Sudhir Sivakumaran, Frederic Lanore, Christophe Mulle, Elodie Richard, Dany Verrier, Giovanni Marsicano, Richard Miles, Enrico Cherubini
Sci Rep. 2012-02-24
10.1038/srep00285

Moving bliss: a new anandamide transporter.
Giovanni Marsicano, Francis Chaouloff
Nat Neurosci. 2012-01-01
10.1038/nn.3011

State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
R. Piet, A. Garenne, F. Farrugia, G. Le Masson, G. Marsicano, P. Chavis, O. J. Manzoni
Journal of Neuroscience. 2011-11-16
10.1523/jneurosci.4297-11.2011

GABAergic and cortical and subcortical glutamatergic axon terminals contain CB1 cannabinoid receptors in the ventromedial nucleus of the hypothalamus.
Leire Reguero, Nagore Puente, Izaskun Elezgarai, Juan Mendizabal-Zubiaga, Miren Josune Canduela, Ianire Buceta, Almudena Ramos, Juan Suárez, Fernando Rodríguez de Fonseca, Giovanni Marsicano, Pedro Grandes
PLoS ONE. 2011-10-11
10.1371/journal.pone.0026167

Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity.
B Gatta-Cherifi, I Matias, M Vallée, A Tabarin, G Marsicano, P V Piazza, D Cota
Int J Obes Relat Metab Disord. 2011-08-16
10.1038/ijo.2011.165

Synergistic post-prandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity
B. Gatta-Cherifi, I. Matias, M. Vallee, A. Tabarin, G. Marsicano, P.V. Piazza, D. Cota
Appetite. 2011-07-01
10.1016/j.appet.2011.05.174

New fat and new neurons: endocannabinoids control neurogenesis in obesity (Commentary on Rivera et al.).
Daniela Cota, Giovanni Marsicano
European Journal of Neuroscience. 2011-05-01
10.1111/j.1460-9568.2011.07684.x

Endocannabinoids and motor behavior: CB1 receptors also control running activity.
Francis Chaouloff, Sarah Dubreucq, Luigi Bellocchio, Giovanni Marsicano
Physiology. 2011-04-01
10.1152/physiol.00050.2010

Emotional consequences of wheel running in mice: which is the appropriate control?
Sarah Dubreucq, Giovanni Marsicano, Francis Chaouloff
Hippocampus. 2011-02-24
10.1002/hipo.20778

Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses.
Megan R. Carey, Michael H. Myoga, Kimberly R. McDaniels, Giovanni Marsicano, Beat Lutz, Ken Mackie, Wade G. Regehr
Journal of Neurophysiology. 2011-02-01
10.1152/jn.00980.2010

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
Cristina Blázquez, Anna Chiarlone, Onintza Sagredo, Tania Aguado, M. Ruth Pazos, Eva Resel, Javier Palazuelos, Boris Julien, María Salazar, Christine Börner, Cristina Benito, Carolina Carrasco, María Diez-Zaera, Paola Paoletti, Miguel Díaz-Hernández, Carolina Ruiz, Michael Sendtner, José J. Lucas, Justo G. de Yébenes, Giovanni Marsicano, Krisztina Monory, Beat Lutz, Julián Romero, Jordi Alberch, Silvia Ginés, Jürgen Kraus, Javier Fernández-Ruiz, Ismael Galve-Roperh, Manuel Guzmán
Brain. 2010-10-07
10.1093/brain/awq278

CB1 receptor deficiency decreases wheel-running activity: consequences on emotional behaviours and hippocampal neurogenesis.
Sarah Dubreucq, Muriel Koehl, Djoher N. Abrous, Giovanni Marsicano, Francis Chaouloff
Experimental Neurology. 2010-07-01
10.1016/j.expneurol.2010.01.017

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance.
Carmelo Quarta, Luigi Bellocchio, Giacomo Mancini, Roberta Mazza, Cristina Cervino, Luzie J. Braulke, Csaba Fekete, Rocco Latorre, Cristina Nanni, Marco Bucci, Laura E. Clemens, Gerhard Heldmaier, Masahiko Watanabe, Thierry Leste-Lassere, Marlène Maitre, Laura Tedesco, Flaminia Fanelli, Stefan Reuss, Susanne Klaus, Raj Kamal Srivastava, Krisztina Monory, Alessandra Valerio, Annamaria Grandis, Roberto De Giorgio, Renato Pasquali, Enzo Nisoli, Daniela Cota, Beat Lutz, Giovanni Marsicano, Uberto Pagotto
Cell Metabolism. 2010-04-01
10.1016/j.cmet.2010.02.015

Bimodal control of stimulated food intake by the endocannabinoid system.
Luigi Bellocchio, Pauline Lafenêtre, Astrid Cannich, Daniela Cota, Nagore Puente, Pedro Grandes, Francis Chaouloff, Pier Vincenzo Piazza, Giovanni Marsicano
Nat Neurosci. 2010-02-07
10.1038/nn.2494

Localization and function of the cannabinoid CB1 receptor in the anterolateral bed nucleus of the stria terminalis.
Nagore Puente, Izaskun Elezgarai, Mathieu Lafourcade, Leire Reguero, Giovanni Marsicano, François Georges, Olivier J. Manzoni, Pedro Grandes
PLoS ONE. 2010-01-25
10.1371/journal.pone.0008869

Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapses.
Joana Lourenço, Astrid Cannich, Mario Carta, Françoise Coussen, Christophe Mulle, Giovanni Marsicano
Nat Neurosci. 2010-01-17
10.1038/nn.2481

Bidirectional regulation of novelty-induced behavioral inhibition by the endocannabinoid system.
Pauline Lafenêtre, Francis Chaouloff, Giovanni Marsicano
Neuropharmacology. 2009-12-01
10.1016/j.neuropharm.2009.07.014

Self-modulation of neocortical pyramidal neurons by endocannabinoids.
Silvia Marinelli, Simone Pacioni, Astrid Cannich, Giovanni Marsicano, Alberto Bacci
Nat Neurosci. 2009-11-15
10.1038/nn.2430

Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmission.
W. Jacob, A. Yassouridis, G. Marsicano, K. Monory, B. Lutz, C. T. Wotjak
Genes, Brain and Behavior. 2009-10-01
10.1111/j.1601-183x.2009.00512.x

Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization.
A. J. Pernia-Andrade, A. Kato, R. Witschi, R. Nyilas, I. Katona, T. F. Freund, M. Watanabe, J. Filitz, W. Koppert, J. Schuttler, G. Ji, V. Neugebauer, G. Marsicano, B. Lutz, H. Vanegas, H. U. Zeilhofer
Science. 2009-08-06
10.1126/science.1171870

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling.
Emma Puighermanal, Giovanni Marsicano, Arnau Busquets-Garcia, Beat Lutz, Rafael Maldonado, Andrés Ozaita
Nat Neurosci. 2009-08-02
10.1038/nn.2369

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
David A. Price, Alex A. Martinez, Alexandre Seillier, Wouter Koek, Yolanda Acosta, Elizabeth Fernandez, Randy Strong, Beat Lutz, Giovanni Marsicano, James L. Roberts, Andrea Giuffrida
European Journal of Neuroscience. 2009-06-01
10.1111/j.1460-9568.2009.06764.x

Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling.
K. Kamprath, W. Plendl, G. Marsicano, J. M. Deussing, W. Wurst, B. Lutz, C. T. Wotjak
Genes, Brain and Behavior. 2009-03-01
10.1111/j.1601-183x.2008.00463.x

Roles of the endocannabinoid system in learning and memory.
Giovanni Marsicano, Pauline Lafenêtre
Behavioral Neurobiology of the Endocannabinoid System. 2009-01-01
10.1007/978-3-540-88955-7_8

Endocannabinoid role in synaptic plasticity and learning
B. Lutz, G. Marsicano
Encyclopedia of Neuroscience. 2009-01-01
10.1016/B978-008045046-9.00816-0

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice.
Douglas Osei-Hyiaman, Jie Liu, Liang Zhou, Grzegorz Godlewski, Judith Harvey-White, Won-il Jeong, Sándor Bátkai, Giovanni Marsicano, Beat Lutz, Christoph Buettner, George Kunos
J. Clin. Invest.. 2008-09-02
10.1172/jci34827

Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses.
Michel A. Steiner, Giovanni Marsicano, Carsten T. Wotjak, Beat Lutz
Psychoneuroendocrinology. 2008-09-01
10.1016/j.psyneuen.2008.06.004

Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity.
Henrik H. Hansen, Birte Krutz, Marco Sifringer, Vanya Stefovska, Petra Bittigau, Fritz Pragst, Giovanni Marsicano, Beat Lutz, Chrysanthy Ikonomidou
Ann Neurol.. 2008-07-01
10.1002/ana.21287

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.
J. Mulder, T. Aguado, E. Keimpema, K. Barabas, C. J. Ballester Rosado, L. Nguyen, K. Monory, G. Marsicano, V. Di Marzo, Y. L. Hurd, F. Guillemot, K. Mackie, B. Lutz, M. Guzman, H.-C. Lu, I. Galve-Roperh, T. Harkany
Proceedings of the National Academy of Sciences. 2008-06-18
10.1073/pnas.0803545105

Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes.
L. Tedesco, A. Valerio, C. Cervino, A. Cardile, C. Pagano, R. Vettor, R. Pasquali, M. O. Carruba, G. Marsicano, B. Lutz, U. Pagotto, E. Nisoli
Diabetes. 2008-05-13
10.2337/db07-1623

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver.
Won-il Jeong, Douglas Osei-Hyiaman, Ogyi Park, Jie Liu, Sándor Bátkai, Partha Mukhopadhyay, Norio Horiguchi, Judith Harvey-White, Giovanni Marsicano, Beat Lutz, Bin Gao, George Kunos
Cell Metabolism. 2008-03-01
10.1016/j.cmet.2007.12.007

Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala.
S. C. Azad, J. Kurz, G. Marsicano, B. Lutz, W. Zieglgansberger, G. Rammes
Learning & Memory. 2008-02-22
10.1101/lm.741908

Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice.
Michel A. Steiner, Giovanni Marsicano, Eric J. Nestler, Florian Holsboer, Beat Lutz, Carsten T. Wotjak
Psychoneuroendocrinology. 2008-01-01
10.1016/j.psyneuen.2007.09.008

Anatomical distribution of receptors, ligands and enzymes in the brain and in the spinal cord: Circuitries and neurochemistry
Giovanni Marsicano, Rohini Kuner
Cannabinoids and the Brain. 2008-01-01
10.1007/978-0-387-74349-3_10

The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction.
Pauline Lafenêtre, Francis Chaouloff, Giovanni Marsicano
Pharmacological Research. 2007-11-01
10.1016/j.phrs.2007.09.006

The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction
Pauline Lafenêtre, Francis Chaouloff, Giovanni Marsicano
Pharmacological Research. 2007-11-01
10.1016/j.phrs.2007.09.006

Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice.
Krisztina Monory, Heike Blaudzun, Federico Massa, Nadine Kaiser, Thomas Lemberger, Günther Schütz, Carsten T Wotjak, Beat Lutz, Giovanni Marsicano
PLoS Biol. 2007-10-09
10.1371/journal.pbio.0050269

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Angelo A. Izzo, , Gabriella Aviello, Stefania Petrosino, Pierangelo Orlando, Giovanni Marsicano, Beat Lutz, Francesca Borrelli, Raffaele Capasso, Santosh Nigam, Francesco Capasso, Vincenzo Di Marzo
J Mol Med. 2007-09-06
10.1007/s00109-007-0248-4

Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex.
b. yuece, a. sibaev, u. c. broedl, g. marsicano, b. göke, b. lutz, h. d. allescher, m. storr
Neurogastroenterol Motil. 2007-09-01
10.1111/j.1365-2982.2007.00975.x

Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice.
M A Steiner, K Wanisch, K Monory, G Marsicano, E Borroni, H Bächli, F Holsboer, B Lutz, C T Wotjak
Pharmacogenomics J. 2007-08-07
10.1038/sj.tpj.6500466

Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants.
A.-G. Corbille, E. Valjent, G. Marsicano, C. Ledent, B. Lutz, D. Herve, J.-A. Girault
Journal of Neuroscience. 2007-06-27
10.1523/jneurosci.3936-06.2007

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Nitin Agarwal, Pal Pacher, Irmgard Tegeder, Fumimasa Amaya, Cristina E Constantin, Gary J Brenner, Tiziana Rubino, Christoph W Michalski, Giovanni Marsicano, Krisztina Monory, Ken Mackie, Claudiu Marian, Sandor Batkai, Daniela Parolaro, Michael J Fischer, Peter Reeh, George Kunos, Michaela Kress, Beat Lutz, Clifford J Woolf, Rohini Kuner
Nat Neurosci. 2007-06-10
10.1038/nn1916

The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.
Tania Aguado, Eva Romero, Krisztina Monory, Javier Palazuelos, Michael Sendtner, Giovanni Marsicano, Beat Lutz, Manuel Guzmán, Ismael Galve-Roperh
J. Biol. Chem.. 2007-06-07
10.1074/jbc.m700678200

Hardwiring the brain: endocannabinoids shape neuronal connectivity.
P. Berghuis, A. M. Rajnicek, Y. M. Morozov, R. A. Ross, J. Mulder, G. M. Urban, K. Monory, G. Marsicano, M. Matteoli, A. Canty, A. J. Irving, I. Katona, Y. Yanagawa, P. Rakic, B. Lutz, K. Mackie, T. Harkany
Science. 2007-05-25
10.1126/science.1137406

Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice.
M. Häring, G. Marsicano, B. Lutz, K. Monory
Neuroscience. 2007-05-01
10.1016/j.neuroscience.2007.02.021

Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice
M. Häring, G. Marsicano, B. Lutz, K. Monory
Neuroscience. 2007-05-01
10.1016/j.neuroscience.2007.02.021

Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.
Katarzyna Maresz, Gareth Pryce, Eugene D Ponomarev, Giovanni Marsicano, J Ludovic Croxford, Leah P Shriver, Catherine Ledent, Xiaodong Cheng, Erica J Carrier, Monica K Mann, Gavin Giovannoni, Roger G Pertwee, Takashi Yamamura, Nancy E Buckley, Cecilia J Hillard, Beat Lutz, David Baker, Bonnie N Dittel
Nat Med. 2007-04-01
10.1038/nm1561

Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function.
Daniela Cota, Michel-Alexander Steiner, Giovanni Marsicano, Cristina Cervino, James P. Herman, Yvonne Grübler, Johanna Stalla, Renato Pasquali, Beat Lutz, Günter K. Stalla, Uberto Pagotto
Endocrinology. 2007-04-01
10.1210/en.2005-1649

Protective activation of the endocannabinoid system during ischemia in dopamine neurons.
Miriam Melis, Giuliano Pillolla, Tiziana Bisogno, Alberto Minassi, Stefania Petrosino, Simona Perra, Anna Lisa Muntoni, Beat Lutz, Gian Luigi Gessa, Giovanni Marsicano
Neurobiology of Disease. 2006-10-01
10.1016/j.nbd.2006.04.010

The endocannabinoid system controls key epileptogenic circuits in the hippocampus.
Krisztina Monory, Federico Massa, Michaela Egertová, Matthias Eder, Heike Blaudzun, Ruth Westenbroek, Wolfgang Kelsch, Wolfgang Jacob, Rudolf Marsch, Marc Ekker, Jason Long, John L. Rubenstein, Sandra Goebbels, Klaus-Armin Nave, Matthew During, Matthias Klugmann, Barbara Wölfel, Hans-Ulrich Dodt, Walter Zieglgänsberger, Carsten T. Wotjak, Ken Mackie, Maurice R. Elphick, Giovanni Marsicano, Beat Lutz
Neuron. 2006-08-01
10.1016/j.neuron.2006.07.006

Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes.
K. Kamprath, G. Marsicano, J. Tang, K. Monory, T. Bisogno, V. D. Marzo, B. Lutz, C. T. Wotjak
Journal of Neuroscience. 2006-06-21
10.1523/jneurosci.0153-06.2006

Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission.
M. R. Domenici
Journal of Neuroscience. 2006-05-24
10.1523/jneurosci.0372-06.2006

How many sites of action for endocannabinoids to control energy metabolism?
U Pagotto, C Cervino, V Vicennati, G Marsicano, B Lutz, R Pasquali
Int J Obes. 2006-03-29
10.1038/sj.ijo.0803277

CB1 and TRPV1 receptors mediate protective effects on colonic electrophysiological properties in mice.
A. Sibaev, F. Massa, B. Yüce, G. Marsicano, H. A. Lehr, B. Lutz, B. Göke, H. D. Allescher, M. Storr
J Mol Med. 2006-02-25
10.1007/s00109-006-0040-x

The emerging role of the endocannabinoid system in endocrine regulation and energy balance.
Uberto Pagotto, Giovanni Marsicano, Daniela Cota, Beat Lutz, Renato Pasquali
Endocrine Reviews. 2006-02-01
10.1210/er.2005-0009

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells.
T. Aguado
Journal of Neuroscience. 2006-02-01
10.1523/jneurosci.3101-05.2006

Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis.
F. Massa, A. Sibaev, G. Marsicano, H. Blaudzun, M. Storr, B. Lutz
J Mol Med. 2005-12-31
10.1007/s00109-005-0016-2

The endocannabinoid system drives neural progenitor proliferation.
Tania Aguado, Krisztina Monory, Javier Palazuelos, Nephi Stella, Benjamin Cravatt, Beat Lutz, Giovanni Marsicano, Zaal Kokaia, Manuel Guzmán, Ismael Galve-Roperh
The FASEB Journal. 2005-10-01
10.1096/fj.05-3995fje

Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
Raffaele Capasso, Isabel Matias, Beat Lutz, Francesca Borrelli, Francesco Capasso, Giovanni Marsicano, Nicola Mascolo, Stefania Petrosino, Krisztina Monory, Marta Valenti, Vincenzo Di Marzo, Angelo A. Izzo
Gastroenterology. 2005-09-01
10.1053/j.gastro.2005.06.018

Cannabinoid CB1 receptor is dispensable for memory extinction in an appetitively-motivated learning task.
Sabine M. Hölter, Magdalena Kallnik, Wolfgang Wurst, Giovanni Marsicano, Beat Lutz, Carsten T. Wotjak
European Journal of Pharmacology. 2005-03-01
10.1016/j.ejphar.2005.01.008

Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons.
M. Melis
Journal of Neuroscience. 2004-11-24
10.1523/jneurosci.3502-04.2004

Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons
M. Melis
Journal of Neuroscience. 2004-11-24
10.1523/JNEUROSCI.3502-04.2004

Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling.
S. C. Azad
Journal of Neuroscience. 2004-11-03
10.1523/jneurosci.2134-04.2004

CB1 cannabinoid receptors modulate kinase and phosphatase activity during extinction of conditioned fear in mice.
A. Cannich
Learning & Memory. 2004-09-01
10.1101/lm.77904

The endogenous cannabinoid system protects against colonic inflammation.
Federico Massa, Giovanni Marsicano, Heike Hermann, Astrid Cannich, Krisztina Monory, Benjamin F. Cravatt, Gian-Luca Ferri, Andrei Sibaev, Martin Storr, Beat Lutz
J. Clin. Invest.. 2004-04-15
10.1172/jci200419465

The endogenous cannabinoid system protects against colonic inflammation.
Federico Massa, Giovanni Marsicano, Heike Hermann, Astrid Cannich, Krisztina Monory, Benjamin F. Cravatt, Gian-Luca Ferri, Andrei Sibaev, Martin Storr, Beat Lutz
J. Clin. Invest.. 2004-04-15
10.1172/jci200419465

Reduced sensitivity to reward in CB1 knockout mice.
Carles Sanchis-Segura, Brandon H. Cline, Giovanni Marsicano, Beat Lutz, Rainer Spanagel
Psychopharmacology. 2004-04-09
10.1007/s00213-004-1877-8

Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity.
Leonid G. Khaspekov, Maria S. Brenz Verca, Lidia E. Frumkina, Heike Hermann, Giovanni Marsicano, Beat Lutz
Eur J Neurosci. 2004-04-01
10.1111/j.1460-9568.2004.03285.x

Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon.
M. Storr, A. Sibaev, G. Marsicano, B. Lutz, V. Schusdziarra, J.-P. Timmermans, H. D. Allescher
American Journal of Physiology-Gastrointestinal and Liver Physiology. 2004-01-01
10.1152/ajpgi.00148.2003

CB1 cannabinoid receptors and on-demand defense against excitotoxicity.
G. Marsicano
Science. 2003-10-03
10.1126/science.1088208

An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice.
Angelo A. Izzo, Francesco Capasso, Anna Costagliola, Tiziana Bisogno, Giovanni Marsicano, Alessia Ligresti, Isabel Matias, Raffaele Capasso, Luisa Pinto, Francesca Borrelli, Aldo Cecio, Beat Lutz, Nicola Mascolo, Vincenzo Di Marzo
Gastroenterology. 2003-09-01
10.1016/s0016-5085(03)00892-8

An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice
Angelo A. Izzo, Francesco Capasso, Anna Costagliola, Tiziana Bisogno, Giovanni Marsicano, Alessia Ligresti, Isabel Matias, Raffaele Capasso, Luisa Pinto, Francesca Borrelli, Aldo Cecio, Beat Lutz, Nicola Mascolo, Vincenzo Di Marzo
Gastroenterology. 2003-09-01
10.1016/S0016-5085(03)00892-8

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis.
Daniela Cota, Giovanni Marsicano, Matthias Tschöp, Yvonne Grübler, Cornelia Flachskamm, Mirjam Schubert, Dorothee Auer, Alexander Yassouridis, Christa Thöne-Reineke, Sylvia Ortmann, Federica Tomassoni, Cristina Cervino, Enzo Nisoli, Astrid C.E. Linthorst, Renato Pasquali, Beat Lutz, Günter K. Stalla, Uberto Pagotto
J. Clin. Invest.. 2003-08-01
10.1172/jci17725

Cannabinoids in energy balance and prospectives in the therapy of obesity
G. Marsicano, D. Cota, G. Stalla, R. Pasquali, U. Pagotto, B. Lutz
CMCCNSA. 2003-06-01
10.2174/1568015033477839

Endogenous cannabinoid system as a modulator of food intake.
D Cota, G Marsicano, B Lutz, V Vicennati, G K Stalla, R Pasquali, U Pagotto
Int J Obes. 2003-03-01
10.1038/sj.ijo.0802250

Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse.
S. C. Azad
Learning & Memory. 2003-03-01
10.1101/lm.53303

The endogenous cannabinoid system controls extinction of aversive memories.
Giovanni Marsicano, Carsten T. Wotjak, Shahnaz C. Azad, Tiziana Bisogno, Gerhard Rammes, Maria Grazia Cascio, Heike Hermann, Jianrong Tang, Clementine Hofmann, Walter Zieglgänsberger, Vincenzo Di Marzo, Beat Lutz
Nature. 2002-08-01
10.1038/nature00839

Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.
Giovanni Marsicano, Bernd Moosmann, Heike Hermann, Beat Lutz, Christian Behl
J Neurochem. 2002-02-01
10.1046/j.0022-3042.2001.00716.x

Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.
Giovanni Marsicano, Bernd Moosmann, Heike Hermann, Beat Lutz, Christian Behl
J Neurochem. 2002-02-01
10.1046/j.0022-3042.2001.00716.x

Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain.
H Hermann, G Marsicano, B Lutz
Neuroscience. 2002-02-01
10.1016/s0306-4522(01)00509-7

Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level.
U. Pagotto, G. Marsicano, F. Fezza, M. Theodoropoulou, Y. Grübler, J. Stalla, T. Arzberger, A. Milone, M. Losa, V. Di Marzo, B. Lutz, G. K. Stalla
The Journal of Clinical Endocrinology & Metabolism. 2001-06-01
10.1210/jcem.86.6.7565

Differential role of the nitric oxide pathway on delta(9)-THC-induced central nervous system effects in the mouse.
Shahnaz Christina Azad, Giovanni Marsicano, Irina Eberlein, Jörg Putzke, Walter Zieglgänsberger, Rainer Spanagel, Beat Lutz
European Journal of Neuroscience. 2001-02-01
10.1046/j.1460-9568.2001.01431.x

Differential role of the nitric oxide pathway on delta(9)-THC-induced central nervous system effects in the mouse.
Shahnaz Christina Azad, Giovanni Marsicano, Irina Eberlein, Jörg Putzke, Walter Zieglgänsberger, Rainer Spanagel, Beat Lutz
European Journal of Neuroscience. 2001-02-01
10.1046/j.1460-9568.2001.01431.x

An in vivo model of hyperacute rejection: characterization and evaluation of the effect of transgenic human complement inhibitors.
Marirosa Mora, Massimo Lazzeri, Giovanni Marsicano, Lubbertus C.F. Mulder, Laura Carraresi, Alessandro Pieri, Alessio Benanchi, Daniela Grifoni, Sandra Nuti, Paolo Bruzzone, Mario Comporti, Raffaello Cortesini, Mara Rossini
Transgenic Research. 2000-01-01
10.1023/a:1008928713058

Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.
Giovanni Marsicano, Beat Lutz
European Journal of Neuroscience. 1999-12-01
10.1046/j.1460-9568.1999.00847.x

Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.
Giovanni Marsicano, Beat Lutz
European Journal of Neuroscience. 1999-12-01
10.1046/j.1460-9568.1999.00847.x

Kidneys derived from mice transgenic for human complement blockers are protected in an in vivo model of hyperacute rejection.
MASSIMO LAZZERI, MARIROSA MORA, LUBBERTUS C.F. MULDER, GIOVANNI MARSICANO, GIOVANNI MARINUCCI, MANUELA BOSCHI, PAOLO BRUZZONE, DARIO ALFANI, RAFFAELLO CORTESINI, MARA ROSSINI
The Journal of Urology. 1998-04-01
10.1016/s0022-5347(01)63617-6

Kidneys derived from mice transgenic for human complement blockers are protected in an in vivo model of hyperacute rejection
MASSIMO LAZZERI, MARIROSA MORA, LUBBERTUS C.F. MULDER, GIOVANNI MARSICANO, GIOVANNI MARINUCCI, MANUELA BOSCHI, PAOLO BRUZZONE, DARIO ALFANI, RAFFAELLO CORTESINI, MARA ROSSINI
Journal of Urology. 1998-04-01
10.1016/S0022-5347(01)63617-6

Factors controlling haemopoiesis in ovine long-term bone marrow cultures.
Giovanni Marsicano, Donika Shehu, Cesare Galli
Veterinary Immunology and Immunopathology. 1997-03-01
10.1016/s0165-2427(96)05599-7

Factors controlling haemopoiesis in ovine long term bone marrow cultures
Giovanni Marsicano, Donika Shehu, Cesare Galli
Veterinary Immunology and Immunopathology. 1997-03-01
10.1016/S0165-2427(96)05599-7